Colief worked for us but is very fiddley if you're BF & also costs £10 a bottle. The chemist normally has it behind the counter so you have to ask for it, but you don't need a prescription.
The instructions say put 4 drops in 2 tablespoons of expressed milk & syringe it into baby. So before EVERY feed (see? Fiddley!) you hand express some milk into a sterilised pot, add the colief & suck it up into a sterile syringe. I didn't bother with 2 tablespoons, I just expressed enough to fill a 5 ml syringe.
Or put it into a bottle of ebm?
The idea is that newborns don't have enough lactase in their gut (the enzyme that breaks down lactose in milk), & excess lactose causes colic. So colief is concentrated lactase.
The colief MUST be mixed with ebm or formula to activate the enzyme, it won't work otherwise. I've heard of people putting it straight into babies mouths, or onto their own nipple (!) but those methods won't work.
I didn't bother if we were out somewhere though. Also I made up a syringe at about 10pm & kept it handy for night feeds (expressed milk can stay at room temp for 6 hrs). You can buy sterilisation bags that go in the microwave for 3 mins to sterilise the syringes etc.
After 3 months he outgrew his colic. We tried infacol & dentinox but they didn't work, gripe water was quite good, & he liked it!
Hope you get some sleep tonight.