Yes, the British get poundingly screwed.
iTunes is possibly the most shameless. Zero distribution costs, but twice the price (IIRC) to download from an American internet connection than a British one.
The Anya Hindmarch site has prices that are about $50-100 cheaper in US dollars than in pounds.
The shipping distance from China is slightly longer to the EU than to the US but not enough to account for the discrepancies in prices. My theory is that British people are used to paying high prices for everything. I've seen American chat boards where people are screaming about paying $140,000 for a three-bedroom "starter" house with a garden in the suburbs of big cities. Companies charge higher prices to British consumers because they can. If nobody bought it, they would drop their prices.