I don't know if I can help at all, but my daughter had a similar-ish problem with settling into nursery and school....
My DD2 was to be atending the nursery that her elder sister was still at. Unfortunately, due to, I guess, a different personality, she hated the nursery DD1 was going to with a passion, to the extent that by the fifth time of trying in the same week she refused to even get in the car, let alone go there!!!
We took the hint and tried somewhere different (hard work as it then meant going to two different places!)
She still found it hard to settle tho, so when DD1 started in reception and a place became available at the attached pre-school, we put her there. Success at last, she loved it and settled down.
It was not to last tho. As much as she loved the pre-school, so she hated the school itself. What I mean by that is, she settled well in pre-school, and seemed to be looking forward to starting 'big school', so we thought it was just a personality clash with the other nurserys. Problem was that when she started in reception, she hated it so much that for the entire year she was there I literally had to drag her in. I didn't even have the option of trying different schools...it's not possible when it is school as opposed to nursery etc.
It all culminated in her last term when even her teacher had had so much that she herself dragged my screaming little girl over the step into the class. I ended up in the headmasters office sobbing along with my daughter.
We had to deal with it by me actually going in each day for 15mins to settle her into the class, and then we finally realised the problem.
She just couldn't face going in amongst so many other kiddies. She wanted to be either among a few, or to be there first, so that she then settled before others arrived and the noise got louder. We only figured that because I would arrive early so that DD got settled before other kiddies arrived and saw me there. I had to be gone before school started so that the other kiddies didn't started requesting their mummies.
I don't know if that helps your situation at all, you seemed to want to know if other have had a similar problem and mine seemed close-ish. What it sounds like could be the problem is possibly the amount of other kiddies and the noise level at the nursery as opposed to play school. In my case, DD2 is much much more sensitive than DD1 and so more sensitive to change, noise, etc. DD1 tends to take things much more in her stride. They are still the same now, and they are now 11(next week) and 9.
Just to say, by the time DD2 went into year one at school, she was fine going in as long as she was holding the teachers hand, and so feeling secure....and now she loves school!!