Hello,
We've just heard from Prof Quenby - she is running a trial for women who have suffered more than two miscarriages and we thought we'd share the details:
The Alife2 trial
Alife2 is investigating whether anti-coagulant (blood-thinning) treatment reduces the risk of miscarriage in women with inherited thrombophilia- a blood-clotting problem.
If you might be interested in taking part in the Alife2 trial, here’s what you need to know:
Who can take part?
You may be able to take part in the trial if a blood test shows that you have inherited thrombophilia and
· You have had two or more miscarriages
· You are aged between 18 and 42
· You are trying for a baby, or plan to try, and are not yet pregnant and
· You are willing to be ‘randomised’ – to be chosen at random – to either the trial treatment or standard care.
What would I need to do?
Participants randomised to trial treatment will be instructed in how to inject themselves once daily with a dose of anti-coagulant in either upper leg or abdomen. Treatment would start at or within 7 weeks of a confirmed pregnancy (based on first day of the last menstruation) and continue until the start of labour/end of pregnancy.
You will be provided with a diary to record when you have administered your treatment or any missed doses.
Where is it taking place?
The following hospitals are currently recruiting patients:
Coventry: University Hospital Coventry
Leeds: St James University Hospital
Nottingham: Queens Medical Centre
Oxford: John Radcliffe Hospital
Southampton: University Hospital Southampton
Sheffield: Jessop Wing
Manchester: St Mary’s
Liverpool: Liverpool Women’s
Birmingham: Heartlands Hospital
Harrogate: Harrogate District Hospital
New centers are opening regularly.
Please ring 02476964 983 to speak to the Clinic Secretary about your interest in this research. Your eligibility for the study will be assessed and if you are eligible you will be given further information about how to take part.