According to the BBC 11 million of us are on a diet in Britain today, yet the vast majority will fail. So what's the best way to lose weight successfully - and keep it off?
What's The Right Diet For You?, a 3-part Horizon special on BBC Two airing this week, will investigate how differences in our biochemistry, psychology and genes may affect our weight.
The programme follows 75 overweight volunteers from across the UK, who will be put on personalised diets to explore three possible causes of overeating: genes; gut hormones; and emotion-related eating. The experiment is led by a team of world-class scientists, one of whom will be joining us tomorrow for a webchat.
Susan Jebb OBE is Professor of Diet and Population Health at Oxford University. She is a nutrition scientist with 25 years' experience of research on preventing and treating obesity and diet-related ill health.
Can science succeed where other diets have failed? Interested in science tips and general weight loss advice? Put your questions to Professor Susan Jebb on Tuesday 13 January between 2 and 3pm, or post your questions in advance on this thread.
You can find out more about the programme here.