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Miscarriage/pregnancy loss

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What sort of thing can they tell you from analysing the tissues?

7 replies

rubles · 06/10/2008 09:44

I have just had my second m/c, for which I had an erpc. They took the tissues for analysis, but I can't remember what she said they would look at.
I think she mentioned something about chromosomes and something else. How much information can I expect, do you think, when I get the results? I don't want to get my hopes up that I'll get a detailed report, and then they tell me that all they looked at was whether it was a molar pregnancy or not.

Any help appreciated.

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loobeylou · 07/10/2008 19:57

I am sure they would be looking at chromosome disorders which account for a large number of MCs - sometimes they can therefore give you a "reason" which brings some peace of mind

sorry for your loss

badknees · 02/11/2008 20:25

Being one of the people who looks at the tissues, 'they' can try to grow the tissues to determine if there are any chromosome problems, abnormalities or rearrangements. "They can also tell if its a molar pregnancy etc, but beware a significant number of samples don't give a result, not because anyone does anything wrong but just because of the nature of the tissue. Also alot of samples give normal results which is somewhat discerting, offering up more questions and no answers. I've also had 8mc now so my thoughts are with you and hope by now that you have some results and hopefully some answers. Big hug.

rubles · 04/11/2008 12:18

Thanks badknees, my results come through in December. I have considered the situation you mention of normal results, and I don't know how I will handle that, it will be very difficult. It might sound weird but I am really hoping for there to be a chromosomal problem, anything else will - like you say - just raise more questions than answers.
Did you get any answers to your miscarriages?

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cmotdibbler · 04/11/2008 12:21

For a second miscarriage, all they will look for normally is whether it is molar or not.

Even for a third its unusual to get them to do chromosomal analysis, and they have to be very careful about taking the sample etc for them to be able to grow the cells on.

Sorry that you are going through this

rubles · 04/11/2008 13:13

Hmm, you see that is another thing, I will be disappointed if they don't manage to grow the cells even though I know that is a very real possibility. Ahh, well, we'll see.
I was surprised they offered any tests at all cmotdibbler, as the miscarriages are not consecutive.

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badknees · 05/11/2008 12:53

Hello rubles, the miscarriages don't have to consecutive to be investigated, depending where in the country you are will depend on the labs policy of what they do if the samples don't grow, you may get a partial result to rule out the most common major chromosome abnormalities or maybe just a no result but please be assured that all samples are treated with great respect and care and everything is tried to get a result (despite the impression some docs may give you). I've never had any answers for my misses, they are generally regarded as chemical pregnancies so there's not much there to investigate, I've had pretty much every test going and still no definitive answers, sometimes in my job you can know a bit too much information.
Please remember that whatever your results, none of it is your fault, there is nothing you could have done to prevent it and sometimes mother nature is a complete bitch and I personally am beginning to wonder if she really is a female being!!

Hope you get some answers and that any problems are easily solved.

rubles · 12/11/2008 10:20

"but please be assured that all samples are treated with great respect and care and everything is tried to get a result (despite the impression some docs may give you)."

Wow, Badknees, you may not realise just how powerful those words are..they have had a real impact. What a lovely, post.

I cry very rarely about this miscarriage but your words did it for me...it's like a release. I am surprised at the reassurance that has given me. I guess it was a worry I didn't even realise I had myself.
It's so nice to think that caring people like you may be doing the investigations on our miscarried babies.

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