Miscarriage - did you have the tissue tested?

[peepsypops]

If so, what was the outcome? Has anyone here ever found the reason for recurrent miscarriage through this?
I'm on my third MMC and just feeling hopeless

I had my 3rd mmc tested but when the results came back the dr told me ‘nothing found, keep trying’. I wish I hadn’t bothered as I had put so much hope into it giving me an answer. But saying that I would probably have regretted not getting it tested too.

I did after my third and 4th. Third came back as trisomy 15 and 4th triploidy.

We had karotyping done after the 3rd and turns out I have chromosome translocations (not of 15 though, that loss was just unlucky).

We have now moved to NHS funded IVF with PGT based on my genetics results.

They did say usually only 5% of people tested will show an issue (with karotyping, the rate is higher with tissue from the pregnancy).

Yes, I did and a chromosomal abnormality was found. It weirdly made me feel better, like it was the natural course of events. I went on to have a normal pregnancy subsequently.
After 3 MC you can get referred to a recurrent MC clinic I think?
Just look after yourself, it's an emotional and physical battering. But there is hope.

Yes and it came back normal, but that was the push we needed to go to the Implantation Clinic in Coventry and stop accepting the ‘bad luck’ story. Successful pregnancy after 4 miscarriages once we had an actual diagnosis.

I had a MMC (as well as a TFMR, a chemical pregnancy and a miscarriage) I had a call about a month later telling me the MMC was a suspected partial molar pregnancy. I didn't even realise they would be investigating what had gone wrong.

Yes, it was a chromosome anomaly. We had karyotype testing, but it was all clear. Like a previous poster, it felt a relief as it was just the natural course of events.

Yes, I had my 4th tested - I wish I had the 3rd tested too but it happened at home and I had no idea which part I would need to try and save and couldn’t face going to the hospital with it in a Tupperware! Mine came back chromosomally normal so pushed me to seek out more opinions on where to go next.

Thank you so much everyone ❤️

Totally - the fear of miscarrying at home this time was crazy. I had random Tupperware scattered around the house in case something happened.

could I please ask you what further investigation did you do and did you get some clarity?

thank you

I'm so sorry about your losses OP
Yes, I had testing.
-1st pregnancy, I'd TTC 4yrs and was 38. NIPT showed patau syndrome (Trisomy 13). I chose TFMR and the autopsy results showed the same
-Next pregnancy, I MC at 7 weeks. They wouldn't do genetic testing, but did send it to pathology. Results showed a foetal tissue and no signs of a molar pregnancy- which were the main things I wanted to know
-3rd pregnancy was from IVF. I MC at 9 weeks and as it was my 3rd loss, they did do genetic testing. It came back as monosomy 22.

I asked to be referred to the recurrent MC clinic, but was told that as I'd had a TFMR for the 1st pregnancy, it wasn't an MC and I didn't qualify- despite the fact that I could have MC'd at any point with T13.

Despite having a very good egg count and every test coming back as clear/normal, it was deemed that my 'old eggs' were the cause of the genetic issues. We have no living children.

Sorry if TMI, but I rang the EPU beforehand and took the products in a sterile jar you can buy from a pharmacy. If you soak products in saline, clots will eventually dissolve whereas products don't. You can store it in the fridge overnight if you can't get the EPU at night and a few drops of saline in the pot helps prevent it drying out. Wishing you all the best op x