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Miscarriage/pregnancy loss

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2 x MMC Secondary Infertility - prednisone help please

2 replies

fleur89 · 25/10/2023 22:12

Hello! 2 MMCs following healthy baby - secondary infertility. First I assumed was bad luck, second got me worried and the tissue was sent for testing. In the meantime while waiting a loooooong time for results I got blood tests done and these came back with all markers clear apart from high nk cells and high activated nk cells in pregnancy. Prescribed by Dr Shehata progesterone, intralipids and prednisone from ovulation.

Today my local nhs hospital contacted me with my dna results from genetic testing... this took MONTHS to come back to me. Turns out the pregnancy had genetic abnormalities - tetraploidy, very rare and nothing I could have done differently was the diagnosis.

So in this situation - armed with this information - what do I do? Do I try without the steroid interventions, given the nhs said chromosome abnormality was the reason? Or do I throw everything at the next try and go ahead with the nk cell reduction plan?

Concerned about side effects of steroids under the nk cell plan so please let me know if anyone has experience that would help reassure me. I'm naturally very petite so any weight gain would be immediately obvious. Moreover, my grandma had osteoporosis and I'm concerned about steroids triggering that.

OP posts:
Meg310532 · 25/10/2024 22:45

What did you decide on?

fleur89 · 31/10/2024 15:39

I went ahead with the steroids, thankfully my only side effect was insomnia for a few months. I now have a healthy newborn baby boy!

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