St marys, shehata, dr thum….. who can help me?

[Hayley220]

I have had basic tests with professor quenby and was told nothing wrong with me and to try again with progesterone (also tried inhixa from positive test and 5mg folic acid) this didnt work and im going through loss number 4 (2nd in a row) as i have a 2 year old.

Now i am wondering do i go private… or can 4 miscarriages really be bad luck? Do i really need to look at nk cells and go on steroids etc.

Just feel very very desperate.
My husband hasnt been very supportive and told me i need to move on (currently awaiting a natural miscarriage or another erpc) told
me i need to get on with life. My parents havent visited me in 2 weeks (they moved an hr and half away) they know im having a rough time
but havent been there. None of my friends have had miscarriages so dont really relate. I just feel so desperately sad, desperate to find reasons why. I am so sad i am missing out on this precious time with my 2 yr old by letting this take over my mind all the time.

I'm sorry to hear about your losses, it's so difficult and painful and I'm sorry it feels so painful.

For me, I went to St Mary's after my second miscarriage in a row in May.

I made this decision after reading the Dr Lesley Regan book about miscarriage. In it she talks about how the timing of the losses is significant - so if you have scans which show your fetuses get to be 7 weeks + they've had a heartbeat which has stopped, and if you keep having losses after this stage, it may well be immune or blood clotting issues. Do you know from scan notes the dates yours had?

Mine were sized at 7.5 and 9 weeks when they stopped growing so I decided to speak to wider family about whether there are immune or blood clotting issues in our family. Sure enough it turns out there are blood clotting issues so I decided on St Mary's as they specialise in this.
Do you have any immuno issues or blood clotting issues personally or in your family?
If so that could help give information about which route if any to try.
My understanding if Dr Shehata also says fetuses that stop growing around 7-9 weeks are often immuno issues which can be treated.

For me, testing came back showing I lack a gene that breaks down clots (I am PAI-1 homozygous) which may well have caused the MC and means I now have to inject heparin (blood thinners) daily in my future pregnancies.
I can't bring myself to try again yet however.

Wishing you well in this next bit of recovery and healing.

Hi @Seaswimmings , can I please ask you where did you do this PAI gene mutation test?
Do you think it is better to see L Regan or Shehata for pregnancy monitoring?

I got the PAI-1 test from Dr Rai at St Mary's as part of their standard blood tests.

Re pregnancy monitoring I have no idea and have never engaged with Dr Shehata as I didnt think my issue is immune system related.. I think at St Mary's I will go in straight after a positive pregnancy test to learn how to inject blood thinners and get prescription, then it's a scan at 6/7 weeks to check viability and discharged into NHS if looking good at that point.
Theres loads of MN threads on Dr Shehata so sure if you look through old threads you'll find the info there.