6 misscarriges in a row ? What now ? ☹️

[ShareLove]

I am unexplained with nhs testing done . 6 early misscarriges in a row and no kids yet , what do I do , where do I go ? Thanks for any advice !! Xx

I had at least 5 before dd1. I was literally getting positive pregnancy tests every cycle after we started ttc but no sticky bean. I had a private appointment booked in and in the meantime started myself on low dose aspirin. By the time I got to that appointment I was pregnant again. The dr told me to carry on with the aspirin and didn’t prescribe anything else. I went on to have a healthy pregnancy. Fast forward 7 years I got pregnant again whilst not actively ttc. By the time I realised I was already further along than I’d got with any of my losses so I didn’t start aspirin. I then had a missed miscarriage at 11 weeks. I did have some testing then but nothing was flagged up. With dd2 I took the aspirin straight away. Make of all that what you will. Never found out what the issue was but there’s definitely something in aspirin if you haven’t tried it yet.

Sorry! Just realised you’ve tried it. My bad

Hi Sharelove. Apologies for the intrusive question or if I missed it in your posts, but are you within a normal BMI? I had recurrent mcs although in my mid to late 30s. I had a successful pregnancy once I got my bmi down to the upper end of the normal range. I think I had undiagnosed pcos (no cysts but other signs). I used intermittent fasting/ healthy diet to reduce insulin resistance and improve egg quality and it worked. Just a thought and may not be relevant to you at all.

@ginandoreos thank you again lovely !
@Notwithittoday oh yes I tired aspirin this time but I still lost it but also got a massive hematoma blood clot which caused more bleeding ? I don’t know if it’s related or now but was also on blood thinners too .
@Chrissmasjammies hey , my bmi is 23.8 so in normal range ,
That’s never been my problem and I don’t have pcos and I have been checked for this and I ovulate every month too I am very healthy weight for my height

@ShareLove sorry for the delay! I'm glad we can be of some help, it really is a mine field!

The beginning of the process for me was as @ginandoreos mentioned. The only thing I would add is that it is possible to see him at Harley Street in London if that is any easier for you to get to and any blood tests that he recommends would be done at The Doctors Laboratory that is close by. Whilst he does initial consultations there if you did see him for scans and also need intralipids that would only be done in Epsom.

Definitely send any results of previous tests that you have had done, I sent everything over by email in advance including any paperwork they sent to me to complete - be as detailed as you can. He will recommend tests to you based on your history. I did everything he suggested but you could try discussing with him which ones should be a priority for you including NK cells. @ginandoreos is correct, they look at the number of NK cells as well as their level of activity.

It's also worth noting that if you do treatment in conjunction with IVF, you would start taking the prednisolone (if recommended) 5 days before your embryo transfer. Your first intralipids if advised would also be at the same time.

I hope this is some help xx

The pred thread just popped up in active for me:

Immune/NK cells - pred thread 29 www.mumsnet.com/Talk/conception/4485946-Immune-NK-cells-pred-thread-29

Xxxxx

@RosieLeeD @ginandoreos thank you both soo much you’re both sooo helpful it’s unbelievable ! I wish I knew you much sooner I had an hour long read of this pred thread ( so many pages 🙈) but I will end up reading all pages ! and it was so interesting and I learnt a lot of information , and also what to ask dr sheata , I mean like I have an idea what he is talking about when things get mentioned as Iv heard it all now on these groups about the different treatments ect xxxx very helpful to know at least xx

@ShareLove you're more than welcome, it's a tough road especially when you feel like you've run out of places to turn or options so I'm glad you feel like this thred and the pred thread have helped you to form an action plan! Xx

Hi ladies,

hope you don’t mind me jumping in. I’m booked in with dr shehata next Thursday for immunes testing - I also have Crohn’s disease.

I have had two early losses 5/6 weeks where only gestational sac seen, no one has mentioned blighted ovum?

Also had 1 chemical and 1 failed FET. I am 31, this all happened from when I was 29!

My IVF doctor keeps saying chromosomal problems but I’m just struggling to accept that when I have been able to produce 22 follicles on meds, 18 fertilised and 10 blastocycsyst.

Surely if I had this I wouldn’t of got such successful results - I know without further testing I won’t know for sure.

My ivf doctor is saying for my to invest my money in PGS testing rather than immunes and he will treat me with steroids?

Did use all see your babies when use were scanned prior to miscarriages?

Look forward to hearing from use ❤️✨

@Hopingformyhappyending hey , sorry you have to be in this sad group ! If I was you I’d go for PSG testing and don’t go to sheata , because if your doctor will treat you with predionsole steroids then you already will have the steroid what sheata would give you anyways 😀 that’s exactly what I am doing , I am not going pga testing but I also didn’t have to go to sheata and my doctor is giving me steroids without having to do expensive tests . I just had my trasfer and I’m on steroids so let’s see what’s the results soon ! Plus if you pga test then you have even better chance of having a healthy pregnancy x

@ShareLove aw thank you for replying and yes unfortunately here but so glad there is many of us for support and advice. Just so nervous them being frozen thawed to be tested and frozen again or something wrong with all and will end up with none !! It’s so scary, with my miscarriages and always just a sac being there I feel doomed !!

usual worries I think we all have, but appreciate your response it’s helped me make a decision, I really hope all goes well for you xx

@Hopingformyhappyending awww I feel you ! But you have so many embryos I am sure some of them will be totally fine if not all! But to be honest , if you wanted to save money , you could just go for the trasfer without PGA testing and just hope for the best 🥰 I’m 100% sure you’ll have some good embryos in there ! I also agree with you about it not being chromosome problems . But again , you have had 2 losses and both completely different , one chemical and one could of been just unlucky ! I had 6 so I can’t blame it on luck anymore . I would personally try 3 times without embryo testing ect before I’d think anything is wrong , it’s very common to have 2 and it be a bad luck ! But ofcourse if I had lots of money if do the testing if it makes you feel better . But personally if I was you right now , I would not test any embryos ( just because of being scared to lose some ) and I’d go for the trasfer with steroids :) and if next one fails then I’d test remaining embryos ! 😊 good luck lovely !

@ShareLove awww I hope so, thanks for some reassurance cause my head is a lonely place at the minute !!

Thats why I’m sort of debating going to see dr shehata in London so then I’m dealing with facts. And do I need to be guided by an immunologist if so? I feel like IVF doctors argue against it sometimes don’t they, doctor has agreed to do an immune protocol either way just need to decide.

I have emailed them about doing Era,, Alice and Emma to test my uterine environment and immune protocol without testing embryos first.

My worry is that my first two miscarriages were the exact same 5/6 weeks only sacs seen on scans. The end will eventually get near for us all and our hearts will be content 🥰

@Hopingformyhappyending hey , I think you had made the right decision about not testing embryos yet ! Just see how the next trasfer goes and if it ends up being the same like an empty sack then you have all the reasons in the world to PGA test the rest of them . And I know what you mean about going to dr sheata so you dealing with facts , but I think it’s well worth saving 1000’s of pounds to try steroid first without seeing sheata . Because you’re lucky , many clinics will never let you have steroids without having all the expensive tests done first , but you’re doctors is willing to let you try them so that’s amaizng ! It’s only the same thing what sheata would give you , predionsole ! Xxx