Borderline / weak positive lupus anticoagulant test

[Ella0909]

I recently had some blood tests to test for clotting disorders. I've only had one miscarriage but both my grandma and mum had been told they have 'sticky blood' and I vaguely remembered a GP mentioning an abnormal blood result when I was a child relating to this so I requested the test.

The lupus anticoagulant came back borderline / weak positive but needs to be repeated in 3 months time. The GP said don't hold off on TTC as even if the test was positive they wouldn't actually treat me any differently in pregnancy unless I've had multiple losses (seems a bit backwards!).

I have carried a healthy pregnancy to full term with zero issues with me or baby...but now I'm even more freaked out than ever that something will go wrong when I get pregnant again.

I know the treatment is daily aspirin and heparin injections...would there be any harm in taking the daily aspirin I wonder?

Does anyone have any experience with this? GP said they can't repeat the tests in 3 months if I'm pregnant because that in itself can obscure results (assuming we catch quickly which we have previously, even if an unsuccessful outcome)

Hi @Ella0909
Sorry for your previous loss...

After 3 losses (14w, termination; 6 weeks and 9 weeks), i had these tests done. They were weakly positive. So I got pregnant again. I lost this 4th pregnancy at 6 weeks. The tests were done again and were massively positive, especially the cardiolipin antibodies. With that in mind, i fell pregnant twice, under the aspirin+heparin+progesterone regimen, but i lost these pregnancies too.

A new marker has appeared in my blood recently, Beta-2-Glycoprotein. The diagnosis of antiphospholipid syndrome has been confirmed 3 times over 9 months.

I am currently undergoing my second cycle of IVF, in order to select normal embryos (after PGS test); when i get a good one, it will be implanted and I will receive higher dose of heparin, likely 60mg per day.

In my case, the weak positivity became a real positivity and a confirmed diagnosis unfortunately...

I'm sorry i can't give you any advice...

Take care xx

S.

@Sophfr17 Thank you for your reply and I'm so sorry for your losses, I can't even imagine going through that so many times, I found one time painful enough :(

I wish you the best of luck and hopefully the higher dose heparin and IVF cycle will help with the antiphospholipid syndrome xx

I spent my first pregnancy so relaxed / ignorant to these problems but feel like the next one will be completely different now I've seen the other side.

Thanks for the encouragement @Ella0909!

Yeah, it is not easy, but life goes on and we adapt, hoping for other solutions every time. I hope IVF + testing the embryos + multiple treatments is going to be our solution :)

I hope everything will be fine the next time your get pregnant. Try not to worry, easy to say.... everything could be fine, maybe the loss you suffered was just sadly due to a bad embryo, if it was an eary loss?

Take care :)

S.