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Miscarriage/pregnancy loss

Low Molecular Weight Heparin

2 replies

SugarSW7 · 20/07/2017 08:28

Hi all,

Sorry to anyone going through the heartache that is loss, recurrent loss any loss. Wouldn't wish it on anyone.
I've had three losses, the most recent one in April and it came back genetically normal.
I've had all testing come back as normal so was referred to St. Mary's for TEG testing, came back normal. So once again, no problem found. However, I saw Dr. Raj, who said that losses after 8 weeks aren't the same as earlier losses in their mechanisms and with the normal karyotype, he's suggesting heparin, despite normal bloods. I'm bit concerned about taking something when I haven't shown to need it. He said that it wouldn't be prescribed to women with an abnormal karyopte loss. And not every woman with three losses as 40% have three that are random chromosomal errors each time.
He is convinced that the normal loss is indication that something is going on. I trust him, but would like to know of any experiences.
Has anyone been on this treatment with no clotting disorder and it be successful?

Thank you.

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ThePopAndCry · 21/07/2017 19:53

Yes, me. Had three early losses and a late loss. After lots of research and tests at different hospitals, it was recommended that I went on baby aspirin, progesterone and tinzaparin (a type of heparin) for the next pregnancy, despite 2 out of 3 hospitals finding that nothing was 'wrong' with me (although, clearly it was!), and one borderline positive APS result at the other hospital.
Anyway, it worked. My ds2 is now 14 months old. I'll never know, but I don't think he'd be here if it wasn't for the three treatments put together. I started the low dose aspirin before I got pregnant and the other two treatment as soon as I got a positive result.
I hope it works for you too. I did a lot of reading at the time and, as far as I can remember, the low dose heparin has been proven safe in pregnancy and doesn't cross the placenta. There is a lot of controversy about the efficacy of baby aspirin but I think Dr Raj is/was an advocate. It might be worth asking about it.

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SugarSW7 · 24/07/2017 14:40

Hi @thepopandcry,

Thank you so much for replying. I'm so pleased that it worked out for you in the end!
Knowing this will help me out massively. Ib tried baby aspirin in my last pregnancy, but it still failed.
Hopefully I'll get pregnant soon and can start the treatment!

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