Other tests for recurrent miscarriage e.g. thyroid etc?

[donttrythisathome]

Hi
I have had 3 mcs now in ten months. After the first two, I was given tests for antiphospholipid syndrome and thrombophilia and referred to to the rmc clinic. After my ERPC yesterday, they sent tissue off to Guys for karotypong.

I asked the consultant if there were any other tests I could do at the GPS e.g. thyroid and he dismissed this as I had no problem getting pregnant. He said I needed nothing else as I have a three year old already and get pregnant, and nothing should be wrong really.

But I don't think that's right.

But I am finding it hard to get clear information (have searched here and online).

Can anyone help clearly explain any pther tests I can get please? I mainly mean simple ones at the GP, although any information at all would be very very gratefully received.

Also I take pregnacare, omega oils, and low dose aspirin (when get a BFP). Is there anything else I should take e.g. Vit D and what dose?

Thanks, desperate for the next one (if I am lucky enough to get pregnant again) to stick around. x

[Bakingtins]

Hi Donttry.
I can only tell you what I've had done and where I'm up to.

After MC 2 I had swabs for infection and a TORCH screen (blood test that looks for infections that can affect pregnancy/immunity status for e.g toxoplasma, rubella, parvovirus etc)
After MC3 I had full blood count and ferritin, TSH (thyroid test that may be elevated and affect pregnancies even if your t4 is normal), panel of tests for antiphospholipid and thrombophilia, day 2 FSH/LH (check for hormonal imbalance and gives idea of ovarian reserve) mid cycle ultrasound scan (said I didn't need any more invasive checks of anatomy as I've carried 2 children successfully) antimullerian hormone (looks for ovarian reserve and PCOS) and karyotyping of both parents.
All of that apart from the scan and the antimullerian hormone was done by the GP, after seeing an RMC consultant privately.
Really hoping to have genetic testing on the baby this time round, as have had natural miscarriages there has never been anything tested previously.
Nothing found on all that lot, so this pregnancy I was on 75mg aspirin, 400mg progesterone twice a day, 5mg folic acid, and a pregnancy multivitamin. Didn't work

I need to know whether baby is chromosomally abnormal or whether I am a serial killer of healthy embryos in which case the next step is reproductive immunology (NK cells and the like) which I am just finding out about. I was recommended the books Coming to Term and Is your Body Baby Friendly? to find out more.

[donttrythisathome]

Hi Baking.
Oh that information is brilliant. Thznk you so much. Hopefully my GP will help- will make an appointment.
And see if I can get the high dose folic acid at the chemist.

I really hope you get the karotyping.

[Bakingtins]

You can only get high dose folic acid on prescription and I think the biggest it comes in anyway is 1mg tablets. I just took loads of the standard 400 microgram ones, they are really cheap.

[donttrythisathome]

Ok thanks!

[squizita]

There is a trial for thyroid going on called 'Tablet' - your local EPU can give you details. Worth it even if you just get tested and found to be fine, for the peace of mind.

[donttrythisathome]

Thanks squiz!

[squizita]

Here is a link with details... you may get the placebo, but even if the worst happens (you have thyroid antibodies, and lose another child) at least you know what medication to ask if you go private. I also think it's a wonderful gift to give future women in our position... all those babies born via aspirin and heparin have a survey like this to thank for their health!

I am going to take part if/when I get the all-clear to try again from Charing x (suspected partial molar = not allowed to TTC for 6 months at least).

www.btf-thyroid.org/index.php/thyroid/research-news/thyroidnantibodies-andnlevothyroxine

[donttrythisathome]

I e-mailed them squiz!
Made a GP appointment too for next Friday. i hope I can persuade them to give me the tests Baking mentioned.

[squizita]

That sounds very positive! :) Best of luck!!