multiple chemical / early miscarriages

[jollytummywobbles]

Think I'm just writing this down to get it out, iykwim.

I've just had my 5th early miscarriage in a row; my 8th since dc1. It was my 13th pregnancy in total. Had 4 early m/c before my child, who was conceived with the help of clomid. I have pcos, take met, and have tried clomid already for #2, but lost on that too. I am currently taking metformin, progesterone, baby asprin, and B6. I've had several cycles using agnus castus, and this one I tried soy isoflavins instead. But I've had the same outcome with both.

We've been for many appointments, and have both been tested for everything they can think of, but there is no cause they can find. I'm just at my wit's end now, and don't actually know what else we can do. I even took time off as soon as I knew I was pg, but it didn't help. Anyone else been in the same situation and has come out the other side? Seems so hopeless right now for us.

hi jolly, I haven't any answers but didn't want to read your post and leave without saying how sorry I am you're going through such a horrendous time.
Miscarriage is heartbreaking and going through so many is emotionally draining.
I had a MC at 10-11wks in March,another at 6 wks in June and have just lost another yesterday(should have been 12 weeks but scan at 10 weeks showed baby died at 8 w6d, I waited to miscarry naturally). We had seen a strong heartbeat at 7 wks and just over 8 wks so were hoping this one would make it.
DH is unsure if we should try again. Because I'm 44 the midwife at the EPU said they wouldn't investigate my recurrent miscarriages as it was probably chromosomal abnormalities due to age. Dealing with the grief for the babies lost but also feeling this may be it and I'll never have another baby makes it all seem quite hopeless.
The thing I try to focus on is my DC,I know you've mentioned you have a DC too. I don't think having children already makes it easier to deal with miscarriage, you still yearn for those you've lost and it doesn't stop you longing for another. However it does give you a reason to carry on . I know that I have to try to be strong for my kids and try to come to terms with whatever the future holds.

So sorry for your losses Jolly. I just lost my 5th in a row too, mc naturally yesterday. Have you had the NK cells test? That's our next plan. Some NHS consultants seem happy to treat empirically with prednisolone, might be worth asking yours about this? Mine won't unfortunately so I'll have to pay for the tests privately to get the treatment.

Its shite that they won't do the tests for you Irishmammy. If you wanted to try again there are things you can try (if you haven't already) such as baby aspirin for underlying clotting issues (I've tried 75mg and 150mg, neither worked for me, but has for others) and coq10 or DHEA supplements (which I've no experience of just heard about them) for improving egg quality. You could also try increasing your folic acid supplement. Obviously I'm not a health professional so you should probably talk to your doc first.

Like Comey said might be worth trying the aspirin but only after you have spoken to your doctor. I had six miscarriages then they put me on 150mg aspirin a day and I had dd in march. They later told me they suggest taking aspirin to anyone over the age of 35. Which pissed me off a bit, that they hadn't suggested this after my first miscarriage never mind the sixth. It might be worth asking them if they will refer you to a more specialist miscarriage clinic we went to st Mary's in London and as a direct result we had dd.

OP I hope you get some help, I feel for you. We would like another dc but I don't know if I can take another miscarriage. You must be a strong person to have been trying for this long.

I've just stumbled on this thread through Active threads. Firstly, I'm so sorry for all your losses

I can't offer advice as I'm two years into my TTC journey and have not managed to conceive yet! However, I did see this article on the BBC website recently and thought it might be of some help.

Geekster I've been wondering whether to request a referral to St. Marys and try the TLC approach on the NHS prior to going private with NK cells testing. I'm just concerned about time passing... I'm 37 and no dc yet. I've also already tried progesterone and aspirin. How long did it take for your referral to come through? How did you find it generally? I can see the NK cells bloke within a couple of weeks so will probably get the ball rolling with him anyway....

Good luck with your ttc journey Frankel, hopefully you will get a sticky one soon. I've seen that article about super fertility, it is interesting. Does seem that many multiple mc sufferers conceive quickly.

Hi Coney I was just 38 when I got refered to st Mary's. And was 39 when I had dd so they still look into it properly even though we are classed as older parents to be. I had an appointment within six weeks of my local hospital referring us. We found them very good. They did a lot more tests than our local hospital did hence they found this clotting thing I had called a thromboelastogram which was slightly elevated hence the aspirin the haematologist at our local hospital didn't really know what a thromboelastogram is so says it all really! They are very through and tend to look 'outside the box', in our experience anyway. Like I say as a result of going we had dd with no further miscarriages inbetween.

I wish you the best of luck and hope you get some help and answers

Thanks Geekster

Coney, so sorry for your losses too.
Thanks for the advice ,I'm seeing my GP tomorrow anyway so I'll discuss it with her. I hope you get some results from your NK cells testing.

Geekster, I know what you mean about none of the health professionals mentioning taking aspirin until after repeated miscarriage. When I was at the EPU after the scan that revealed the baby's heart had stopped beating the midwife asked if I had been taking it, despite the fact no one had suggested it and I'd been there for a scan at 8 weeks only a fortnight before when they went through my full history again including any medication I was taking. I'm always going to wonder if it might have helped, I just wish the doctor had mentioned it even after the second miscarriage.

Frankel, that article is interesting. I just wonder how they can diagnose it in vivo and what could be done to treat it.
I hope you get your BFP soon!