Night sweats worsening on HRT, should I review my medication?

[AliasGrape]

I’m coming up to 47 and started HRT 2 years ago. Reasons at the time were low mood, rage, itching, still regular periods but incredibly heavy (always have been but this was a step up even from that), brain fog, anxiety.

Its sort of helped with some of it - definitely the itching, I still get a flooding day or 2 of periods but not as bad overall, I’d say brain fog has lifted a little. I had to get other medication for the low mood and anxiety but together something is working there.

I’ve now started with the night sweats - they’re horrendous. Theyre worst when I’m on my period which is still happening regularly although not AS regular as it was and overall a bit shorter, still flooding sometimes though and the combination of that last night and waking up literally feeling like I was lying in a puddle I was that sweaty - it’s just been a horrible night and leads me to question of the HRT is even doing anything?

I suppose my question is is it time to switch something up with the medication (I’m using the Lenovo spray and progesterone tablets), or are you still going to get new and worse symptoms even with the medication? Is there something else I could/ should be doing as well - weather it be diet or supplements or whatever.

And just after some solidarity really - I’d heard about the night sweats before, and experienced something similar when I was taking fertility drugs before DD, but nothing like this I hadn’t realised how horrible it could be.

What dose of oestrogen? Sounds like you need to increase it.

Sorry I should have said it’s the lenzetto spray and I do 3 sprays which apparently I can’t increase from. I did start off with the gel though and feel like I noticed more difference on that - I’m just not convinced it’s being absorbed/ doing much.

Perhaps I’ll try on my thigh instead of arm first - shouldn’t make a difference but maybe it will and if not speak to GP about it another method would help.

I have Lenzetto and was told it has a short “half life”. So it is metabolised quickly. I have two sprays in the morning and two in the evening which seems to keep me balanced (along with evening testosterone and mirena coil)

Increase the dose but if you can't with the spray change back to gel.

Do the patient instructions say 3 sprays max?
How much estrogen is that and how does it compare to 3 or 4 pumps of gel?

@AliasGrape This is on the web.

Each spray delivers 90 microliter of transdermal spray, solution containing 1.53 mg of estradiol (equivalent to 1.58 mg of estradiol hemihydrate).

1 pump of gel is 0.75mgs of estrogen.
So Lenzetto is twice the strength.

Therefore, you are right that 3 sprays is the max.

Maybe try gel?

Thanks @hirsuteonHRT thats interesting I’ll try that.

I’ve never been offered testosterone- one of the things that came out from my fertility tests back when I was doing that (so 10+ years ago) was that I had very low testosterone- I’ve no idea if that’s still the case or what impact that would have but it’s something I can look into.

@JinglingSpringbells yes maybe the gel would be better, I did start out on the gel and it seemed to be working but obviously hadn’t started with the night sweats back then.

I have to have the testosterone privately annoyingly but it’s not expensive in itself (maybe £100 a year), it’s the private blood test and check up appt that cost (my clinic wants you to test annually to avoid overdoing it)