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Help! 2 week wait referral- Post-menopausal bleeding and thickened endometrium after starting HRT

6 replies

MustUseAName · 02/04/2026 15:28

I’m really stressed as just had a 2 week wait referral due to thickened endometrium. Do you think I need to really worry or just worry a little bit?

I’m post menopausal, last period probably pre-Covid. (It’s so long ago I can’t remember!). I was still having trouble sleeping, hot flashes, etc so started patches and oral progesterone 7 months ago. Since then I’ve been bleeding twice a month, getting cramps and bloating.

The GP sent me for an internal ultrasound yesterday and I got the abnormal result today.

If I’d known this would happen, I’d have put up with the menopause symptoms! This has been such a shit week!

OP posts:
ClaireEclair · 02/04/2026 15:30

I’m not on HRT but a friend is and had the same issue. She had tests after the scan and all was okay. It was to do with her HRT and they had to adjust it. She’s been fine since but she was really worried too.

overwork · 02/04/2026 15:45

in my department we transfer all patients with a thickened endometrium to gynaecology urgently. Vast majority just need their HRT dose altering. I can’t say for certain which category you fall into obviously but hopefully it’s just that

JinglingSpringbells · 02/04/2026 16:40

MustUseAName · 02/04/2026 15:28

I’m really stressed as just had a 2 week wait referral due to thickened endometrium. Do you think I need to really worry or just worry a little bit?

I’m post menopausal, last period probably pre-Covid. (It’s so long ago I can’t remember!). I was still having trouble sleeping, hot flashes, etc so started patches and oral progesterone 7 months ago. Since then I’ve been bleeding twice a month, getting cramps and bloating.

The GP sent me for an internal ultrasound yesterday and I got the abnormal result today.

If I’d known this would happen, I’d have put up with the menopause symptoms! This has been such a shit week!

It probably just means you need slightly more progesterone each month for the dose of the patch or you haven't settled down into the continuous regime.

Anything serious like endo cancer is extremely rare in women using HRT. If you've been taking the progesterone as prescribed it's likely to be a 'blip'.

Try not to worry. It's normal to take 6 months for continuous HRT to work fully and become a 'no bleed' sort and you're just a few weeks over that time.

Endometrial cancer is something that can happen in a very small number of women after a year on only estrogen - and that's not you.

puddock · 02/04/2026 17:16

Might be useful to think in advance about whether you are happy in general with the progesterone part of your hrt. I has something similar last year (unexpected bleeding on continuous hrt) but was really not tolerating the oral progesterone well so didn't want to up it. I now have a mirena-type IUS delivering the progesterone instead and (after a few weeks settling) it has been much better, and my endometrium has stayed thin since. It may be something gynae will suggest to you when you're seen?

justasking111 · 02/04/2026 17:17

ClaireEclair · 02/04/2026 15:30

I’m not on HRT but a friend is and had the same issue. She had tests after the scan and all was okay. It was to do with her HRT and they had to adjust it. She’s been fine since but she was really worried too.

Ditto my colleague, we all worried about her until she got the results.

MustUseAName · 03/04/2026 10:56

Thank you all so much for your reassurance x

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