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Menopause

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Does anyone have any knowledge of high SHBG/high estrogen/high testosterone?

4 replies

CremeDeSudo · 01/04/2026 08:30

Recently paid for bloods to be done and came back as v high estrogen, highish testosterone and highish shbg.

Had tests done as was trying to understand my lifelong low libido issues and expected low testosterone!

Some googling suggests that high shbg is inhibiting my free testosterone and to try a low dose of testosterone.

I have a GP appointment next week but don't have a lot of faith in them to prescribe it.

Just wondered if anyone has any knowledge/experience of this?

TIA!

OP posts:
RosieHighlander · 01/04/2026 09:31

I had blood tests done recently too which came back as high estrogen (1515pmol) and high SHBG (200 nmol/L), so very interested in following replies here! My testosterone was 0.95 nmol/L.

JinglingSpringbells · 01/04/2026 09:32

What is SHBG?

You're right that your GP is unlikely to help as this is a very specialist area. Even testosterone is limited in availability in the NHS. And it has to be balanced with estrogen.

I think you'd need to see a specialist and there is also the question of whether the blood test you had is accurate.
Estrogen levels vary by the day and many specialists don't do them except perhaps for fertility/ early menopause.

Was this a blood test you sent off by post?

CremeDeSudo · 01/04/2026 10:05

SHBG = Sex Hormone Binding Globulin

I'm definitely a challenging case. I've had a hysterectomy (but kept hormones), been on HRT for a few years now. I had to get referred to the menopause clinic because I was having issues with increasing estrogen and fought to be allowed progesterone too. 99% of issues OK now, just occasional night sweats.

Test was a finger prick check from Medichecks. They've suggested a repeat blood test from the Dr as estrogen levels alarmingly high!

I've been down a rabbit hole with this and believe high SHBG is often associated with high estrogen, and also starting the contraceptive pill young (I went on it at 14 due to heavy/painful periods). If it's high it can stop the body utilising estrogen and testosterone properly.

I'm now suspicious that going on the pill masked problems, and caused further problems!

I really don't want to wait another c18 months for a menopause clinic referral and will likely go private, but just wondered if there were any similar experiences here!

OP posts:
CremeDeSudo · 02/04/2026 20:29

Bump

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