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Menopause

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Oestrogel arm/thigh application rotation

17 replies

Wonderbug81 · 22/03/2026 11:13

I've been peri for 4 years, fairly steady management for a while with HRT (oestrogel, utrogestan). Recently (past 3 months) had v high anxiety and low motivation etc. Blood tests just back and it says testosterone is extremely low.

Also says Estradiol is 97 pmol even with 3 pumps Oestrogel.

Waiting for menopause doctor appt to discuss options but having done some research I've just found out that you're supposed to rotate the location between thigh and arm. I've been using my inner thigh for at least a year.

How much might this have affected things? Anyone had an improvement when they started rotating location or is it likely that I'll need to increase dose too?

Don't want to increase dose unnecessarily because that can often come with its own side effects!

OP posts:
JinglingSpringbells · 22/03/2026 11:30

You don't need to rotate the application site.

There's a lot of mixed info on this and it really makes no difference if you rotate or not. (I've used gel for over 15 years.) I use my arms but sometimes the gel does make the skin a bit dry so I them change to my inner thighs.
However, if you want to experiment by swapping, it's easy to do that.

Also, blood tests are really not accurate. There are many scientific papers on this (online) where it's been shown that blood tests are not reliable. My consultant has never used them and says (which is what the research says) that the only reliable test for estrogen would need to be done constantly over 24 hours.

One thing you could try as you're using 3 pumps is to split the dose morning and night. So 1 pump on each thigh in the morning, and 1 pump in the evening.The British Menopause Society suggest this for higher doses. The reason is that you have to spread the gel thinly. If you're putting more than 1 pump on each inner thigh it may not be spread thinly enough. (I spread 1 pump between both legs or arms.)

How are you applying it at the moment?

Wonderbug81 · 22/03/2026 12:07

Thanks. I don't normally pay much attention to these tests either but given I've had anxiety symptoms/high heart rate for 3 months alongside various other symptoms and other specialists discounted other possibilities e.g. cardiologist tested and said most likely to be hormones as no other issues with heart) I think there is some merit in this particular test. Even without the test my symptoms point to needing more oestrogel.

I apply with a plastic spatula so I can get as much on the skin vs hands as possible, leave to dry for 5 mins, don't apply too thinly or thickly. Apply 1.5 pumps across the largest expanse of each inner thigh as possible but will try 1 pump on each thigh and 1 pump on one arm from now on. Doesn't really suit to split the dose across the day.

OP posts:
JinglingSpringbells · 22/03/2026 13:13

Wonderbug81 · 22/03/2026 12:07

Thanks. I don't normally pay much attention to these tests either but given I've had anxiety symptoms/high heart rate for 3 months alongside various other symptoms and other specialists discounted other possibilities e.g. cardiologist tested and said most likely to be hormones as no other issues with heart) I think there is some merit in this particular test. Even without the test my symptoms point to needing more oestrogel.

I apply with a plastic spatula so I can get as much on the skin vs hands as possible, leave to dry for 5 mins, don't apply too thinly or thickly. Apply 1.5 pumps across the largest expanse of each inner thigh as possible but will try 1 pump on each thigh and 1 pump on one arm from now on. Doesn't really suit to split the dose across the day.

Edited

I genuinely think this may be about getting better absorption. I use 1 pump only and apply that between both arms or both thighs. I'd struggle, personally, to apply 1.5 pumps to inner thighs and get a thin layer that dried quickly.

On 2 pumps I was splitting the dose am and pm, because initially I was getting 'morning sickness' feelings with 2 pumps at once.

Give it a whirl.

CluckerHam · 22/03/2026 13:21

Not sure if this is relevant to you, but I recently saw an instagram reel saying that you shouldn’t really rub the gel in… just a quick swipe over and back then wait for it to absorb. I’m not using the gel anymore but I think i was rubbing it in quite a bit when I did use it.

Also, you could consider switching to patches to see if you get better absorption. I prefer Estrodot rather than Evorel

NippyNinjaCrab · 22/03/2026 13:43

Jeez I hope i am applying it correctly. I apply 3 pumps on my right upper arm with one finger and its not really spread thinly, I just wait till it dries before getting dressed. I have no idea if this is right or not now! Any residue left is wiped on my inner thigh. I've been doing this for a while.

Wonderbug81 · 22/03/2026 14:10

CluckerHam · 22/03/2026 13:21

Not sure if this is relevant to you, but I recently saw an instagram reel saying that you shouldn’t really rub the gel in… just a quick swipe over and back then wait for it to absorb. I’m not using the gel anymore but I think i was rubbing it in quite a bit when I did use it.

Also, you could consider switching to patches to see if you get better absorption. I prefer Estrodot rather than Evorel

Thank you. I use a flat spatula kind of thing (it's actually a platerer's tool 😁) and leave a thin layer. It's possible the layer is too thin though.

OP posts:
Wonderbug81 · 22/03/2026 14:13

NippyNinjaCrab · 22/03/2026 13:43

Jeez I hope i am applying it correctly. I apply 3 pumps on my right upper arm with one finger and its not really spread thinly, I just wait till it dries before getting dressed. I have no idea if this is right or not now! Any residue left is wiped on my inner thigh. I've been doing this for a while.

Do you have any symptoms? Usually easiest way to tell if it's OK. There's also an element of, perhaps you actually need 2 pumps but because of the way you apply 3 pumps gets the equivalent of 2 pumps to you as it counters the poor absorption.

I think it's all trial and error. I imagine different types of skin etc also have an effect.

OP posts:
JinglingSpringbells · 22/03/2026 14:48

If this helps, in older versions of the pump, the leaflet advised on how much skin was needed to spread the gel.

The template was the leaflet which was/ is a large A4 size.
So that is the amount you ought to be covering in a thin layer.

You don't rub like mad, as if you're cleaning a window (!) but you do need to smooth it up and down with a few strokes so it's not so tacky as when first applied.

@NippyNinjaCrab I can't see how 3 pumps can be spread on one upper arm because you're only supposed to apply it on the outer arm, not the inner side near your breasts. Isn't it taking ages to dry?

Wonderbug81 · 22/03/2026 15:45

JinglingSpringbells · 22/03/2026 14:48

If this helps, in older versions of the pump, the leaflet advised on how much skin was needed to spread the gel.

The template was the leaflet which was/ is a large A4 size.
So that is the amount you ought to be covering in a thin layer.

You don't rub like mad, as if you're cleaning a window (!) but you do need to smooth it up and down with a few strokes so it's not so tacky as when first applied.

@NippyNinjaCrab I can't see how 3 pumps can be spread on one upper arm because you're only supposed to apply it on the outer arm, not the inner side near your breasts. Isn't it taking ages to dry?

Is that for 2 pumps?

I think I'm OK as the plasterer's spreader helps get it quite even as a thin layer. I read about this tip on another forum as a way of getting as much on the area as possible.

OP posts:
JinglingSpringbells · 22/03/2026 16:02

Wonderbug81 · 22/03/2026 15:45

Is that for 2 pumps?

I think I'm OK as the plasterer's spreader helps get it quite even as a thin layer. I read about this tip on another forum as a way of getting as much on the area as possible.

I assume it's for 1 pump each upper arm.

I know everyone has their own method.

I pump 1 pump into my palm. I press my palms together lightly just enough so the gel divides between my two hands then rub it over each upper arm.
If anything is left I wipe my palms over my inner thighs.

There are numerous methods online.

One new method is saying apply from shoulder to wrist, yet years ago it was upper arm (or inner thigh) only as it was supposed to be absorbed more by fat and there is little in the forearms.

NippyNinjaCrab · 22/03/2026 17:46

@JinglingSpringbells I would say approx 15 mins and I brush my teeth and cleanse during that time. I better read my leaflet, I was told upper arm and shoulder nothing was specified only outer arm but it doesn't go anywhere else until dry tbh. 3 pumps is quite a thick layer yes.

Spaghettea · 22/03/2026 17:49

You're all doing better than me. I just put a bit on, when I remember, after I've got my pyjamas on.
Still on my first bottle 18 months in.

NippyNinjaCrab · 22/03/2026 17:49

I've definitely been applying it incorrectly with 3 pumps in one area. It says from wrist to shoulder, outer arms or inner thigh. One pump each area.

HollywentLightly · 22/03/2026 19:17

After reading oestrogel patient information from across the world, for my three pumps I spread it across my thighs, lower belly and bum. I'm short so outer arms and inner thighs just don't have the acreage i need and it's hard enough to do once a day, nevermind twice. I certainly feel I'm getting a better dose this way.

JinglingSpringbells · 22/03/2026 22:08

NippyNinjaCrab · 22/03/2026 17:46

@JinglingSpringbells I would say approx 15 mins and I brush my teeth and cleanse during that time. I better read my leaflet, I was told upper arm and shoulder nothing was specified only outer arm but it doesn't go anywhere else until dry tbh. 3 pumps is quite a thick layer yes.

@NippyNinjaCrab I'm wondering if the leaflets have changed or different packaging has different leaflets?

I've used it for years and the 'whole length of arm' was never part of the guidance. It was outer upper arms (and shoulders) or inner thighs.
I'll read the leaflet again out of interest.

It takes mine about 60 seconds to dry- that's one pump divided between 2 outer upper arms. I was doing 2 pumps for years but have reduced to one.

JinglingSpringbells · 23/03/2026 09:22

@Wonderbug81 @NippyNinjaCrab

For info- I've just checked the leaflet partly to see if anything has changed .

Instructions say -

Apply to the shoulder, outer arm or mid-inner thigh.
(Nothing about the arm to wrist.)
For 2 pumps use arms or legs, for 4 pumps use arms and legs.

It says allow to dry for 5 minutes- so that is a guide as to how long it takes if you're spreading it fairly thinly.

NippyNinjaCrab · 23/03/2026 14:27

JinglingSpringbells · 23/03/2026 09:22

@Wonderbug81 @NippyNinjaCrab

For info- I've just checked the leaflet partly to see if anything has changed .

Instructions say -

Apply to the shoulder, outer arm or mid-inner thigh.
(Nothing about the arm to wrist.)
For 2 pumps use arms or legs, for 4 pumps use arms and legs.

It says allow to dry for 5 minutes- so that is a guide as to how long it takes if you're spreading it fairly thinly.

I didn't take the leaflet out of my box, I checked it online so I will check the box. That's very misleading online isnt it if it is different info. I have applied it as you recommended ded this morning, I used the cap to apply, did upper outer arms and shoulder a pump each and one inside thigh with the residue on the other thigh. Hopefully that will help with proper absorption now. I do have an appointment booked for 1st April for a review of my HRT, this was because I am having symptoms and I thought I might need an increase. Now I think I have been applying it wrong.

Thank you as always for your expertise and advice on the menopause section xx

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