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Utrogestan vaginally, is it effective?

37 replies

Oakiedoakie · 27/01/2026 14:37

Hello, I'm thinking of switching to using utrogestan vaginally but am just a bit anxious about how safe and effective it is? Those of you ladies that do this, have you found it to be ok, long term? Really don't want to get a mirena.

OP posts:
70percent · 06/10/2026 12:14

Oakiedoakie · 06/10/2026 11:01

Yes, I'm using the round utrogestan tablet. The menopause gp said this was fine.

Thanks. Is it with an applicator? I only learnt after my appt I could have asked for pessaries but it sounded like the GP didn’t think that was an option. Is it very messy?

70percent · 06/10/2026 12:15

@Oakiedoakie also how is your mood and any other symptoms? Would you recommend it?

Oakiedoakie · 06/10/2026 12:43

To be honest, the main reason I started using it vaginally, was because of the massive hair loss I was having, which does seem to have lessened, touch wood. I think if I had to go back to using utrogestan orally, I would probably just stop hrt altogether. Just my experience.

OP posts:
Oakiedoakie · 06/10/2026 12:49

Sorry, just saw your question about the applicator. No, I just use my finger.

OP posts:
70percent · 07/10/2026 22:32

Sorry one more question - I’ve got vagirux pessaries of oestradiol that I’m supposed to use two nights a week. Do you take something similar and do you now take them in the morning instead?

over50andfab · 07/10/2026 23:54

70percent · 07/10/2026 22:32

Sorry one more question - I’ve got vagirux pessaries of oestradiol that I’m supposed to use two nights a week. Do you take something similar and do you now take them in the morning instead?

When I switched to inserting uterogestation vaginally instead of taking it orally I inserted the estradiol pessaries in the morning. However, if you’ve only just started using them and if dry you might find they drop out again, at least initially, which is why inserting at night is better. It can help to insert with just a little moisturiser to help them stick to the vaginal walls.
Another way which some women do is insert the utrogestan up high and the estradiol pessaries about halfway up - which is closer to the urethral tract anyway to help with any bladder issues like frequency.

Edit I’ve just seen that I already posted about this further back in the thread

ifonlytheydlisten · 08/10/2026 00:12

Orally gave me massive bloating gut aches. Tried a few times.

Oakiedoakie · 08/10/2026 01:45

I use a little ovestin on the outside bits and vagifem pessaries in the morning.

OP posts:
70percent · 08/10/2026 07:45

Thanks @over50andfab and @Oakiedoakie I’ll use them in the morning.

70percent · 21/10/2026 08:08

I’ve now been using the utrogestan 100mg round pill vaginally for two weeks. I’ve bought some applicators or used my finger. My sleep and / or night dreads have definitely been better though my mood in this second week is less good.

I still wake up to pee at 5ish and then when I go to the loo at 7.30am or so there are white bits from the progesterone in the water. Some of you said how messy it can be. Is it still effective and being dissolved, do we know? I was just worrying it means not all of it is being absorbed.

thanks all

over50andfab · 21/10/2026 15:24

If you are seeing remnants the following day it's likely the active ingredients will have absorbed in leaving the residue (added ingredients making up the product). When used vaginally it doesn't affect mood or sleep in the same way as it might orally.

Venice93 · 21/10/2026 15:31

Didn't get on with it vaginally. Messy (as pp said); and also did something to my internal musculature that meant that I started having stress incontinence issues. I thought it was unrelated until I stopped (couldn't stand the mess) and it all went away.

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