Vaginal Oestrogen and Breast Cancer improves survival

[ipredictariot5]

great to see that finally this is actively being looked at and researched.
https://www.independent.co.uk/news/health/breast-cancer-treatment-menopause-estrogen-cream-symptoms-b2764450.html

You have to look carefully in that report. For hormone sensitive breast cancer … of which 70-80% of breast cancers are- there is no statistically significant benefit. Research sponsored by the estrogen cream companies by any chance?

It's quite odd because we're told that there is no absorption systemically with vaginal estrogen - or such a tiny amount that it's not relevant.

If it was was absorbed systemically, women would need to take progesterone occasionally to reduce the womb lining. This was suggested years ago but has now been changed to unnecessary.

I'd like a link to the actual study because it appears that the results were based on just over 800 women and there's no detail about all the other factors that may have been a factor.

It's badly reported as it talks about hormone-sensitive and then estrogen - driven. And the photo is of pills not cream!

https://ascopubs.org/doi/10.1200/JCO.2025.43.16suppl.578#

The report.

It's really interesting. Maybe the cream was not the important factor. Maybe women using it were more active, resulting in better immune systems...who knows?

It was purely observational not a placebo controlled trial.

I got it through my NHS prescribing updates which I just took to mean as a prescriber to go ahead. I do not look after a patient group I would prescribe it to but know there is so much misinformation about any sort of oestrogen in breast cancer that I would share it

I'm a bit confused.
Are you posting this as a GP, saying the NHS will now prescribe to women they didn't before based on this research?

It is good news and we need more research in to these areas… thanks for sharing.

Not a GP. Not sent as an NHs instruction just as education