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Has anyone just given up on HRT as just not helping them?

30 replies

BusinessScrub · 16/04/2025 15:25

I've been on HRT for two months (gel + progesterone tablets). It's for an irritable bladder, not moods or tiredness and I am close to giving up.

There's a whole confluence of things I've posted about before - have to take the progesterone vaginally and that's irritating my bladder so what's the point and I hate progesterone - but basically, I feel much worse. I am more tired, more depressed and less energetic. It is not a miracle cure for me. Possibly I am less anxious, but that's it.

Any advice gratefully received

OP posts:
BotoxOrPuffins · 21/10/2026 22:10

I was on HRT for nearly 2 years and came off it 4 months ago as it started to make me feel awful. I would give it a bit longer before you change it or come off it.

LuckyCharmz · 21/10/2026 22:36

I also couldn’t tolerate progesterone in any way, but like my mirena coil.
as others say, worth trying a different form, it can be trial and error.

BooseysMom · 25/10/2026 10:15

I tried Estrogel and Utrogesten then when that didn't work I tried Evorel patches but I just continued feeling the same as always. I've always had bad PMT and my periods are getting harder to cope with but aren't that lengthy with it all over in 3 days. I was given the option of the Mirena coil but can't really see the point as I'm 54 and surely at the end of my periods. Synthetic hormones don't help me as the pill always made me suicidal so I had to stop taking it. With HRT it's just more of that so bollocks to it all!

Sarajane3 · 26/10/2026 10:25

Can I ask how old you are. I am 53 never really had pms but am just physically and mentally exhausted ALL THE TIME ALL DAY EVERY DAY!!! this is like chronic fatigue. I can't wait for bed time to come around again. I have just gone up on my antidepressants as feeling so low which I basically think is im so sick of feeling shit all day every day. I get no respite. Dizziness every single day sometimes so debilitating I have to go to bed it's ruining my life. Waiting for ent appointment as I think could be vestibular problem have become so sensitive to noise even someone clearing their throat or turning the page of a book goes through my head like a hand grenade

BooseysMom · 27/10/2026 20:13

Sarajane3 · 26/10/2026 10:25

Can I ask how old you are. I am 53 never really had pms but am just physically and mentally exhausted ALL THE TIME ALL DAY EVERY DAY!!! this is like chronic fatigue. I can't wait for bed time to come around again. I have just gone up on my antidepressants as feeling so low which I basically think is im so sick of feeling shit all day every day. I get no respite. Dizziness every single day sometimes so debilitating I have to go to bed it's ruining my life. Waiting for ent appointment as I think could be vestibular problem have become so sensitive to noise even someone clearing their throat or turning the page of a book goes through my head like a hand grenade

So sorry you're suffering like that. I'm the same. I feel ill constantly and can't wait to go to bed. It's like my life is over. I have aching, burning down below, itching all over and insomnia every night. Also sweating now which is new. None of my symptoms were relieved by hrt and so I gave it all up. I've gone back to the doctors and see a different nurse every time. The latest thing is to try the coil again but what's the point, I haven't had a period for 6 weeks! When I do get one it will be horrendous I know.
The noise thing you have is interesting as I have developed the same thing only not as severe. But earlier on DS made a noise and my stomach turned over with fear as it sounded so loud but it wasn't!
I hope you find some answers anyway. Good luck.

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