Progesterone - feel like throwing myself in the nearest canal

[TwinklyOliveStork]

Hello,
I am on evorel sequi and everytime the patch changes from estrogen to the estrogen progesterone I feel so mentally low, argumentative, like everything is too much hassle and moments of panic. Fine a few days in, and then when it comes to coming off it and back to estrogen only the same happens again. Everything else it has fixed, periods no longer coming every 6 days, no hot flushes or migraines. Nothing else at all.

Is this normal? And is there any way around it? Or alternatives anyone knows of.

Thanks in advance

Are you still having periods? How old are you if you don't mind saying?

If your periods weren't regular or had started to slow down (and as you seem to stabilise a few days in) can you ask about moving to the combined patches (Conti) although you may get irregular bleeding with these if you're still having periods.

Or, you could perhaps use the Mirena coil for the progesterone part of your HRT? Or try oestrogen patches with Utrogestan capsules 12 days each month (supposed to have less side effects as it's biosimilar)

Hi, thanks for your response.

I am 39, and periods came really often, irregular and heavy, lasting longer. They are now averaging every 5-6 weeks and lasting the expected 7 days or less and lighter than they had been.

They started me with estrogen patches and utrogestan but migraines with aura was bad, so they swapped me to the sequi patches. I have debated the mirina coil and really given it thought. Had a bad experience with it pre kids, but think perhaps it would be better now. My thoughts are that it could make it all a bit more level - but not sure if that is the case?
I have rang local clinics who won't fit one as HRT, have been referred to gyny due to my age, however that was last September and I still low down on the list. I know I am younger than many, but following the same pattern as my mum and nan by the looks of it

Mirena has the benefit of reducing or even stopping your periods. Might be worth seeing if you can get it fitted via family planning by saying you want it for contraception (they won't do it for HRT!)

Can you afford to see a menopause specialist privately? After 1 appt they can usually advise your GP so you can get NHS prescriptions.

You do need specialist help as you're young to be in peri.

There are many other options.

One is the Mirena coil, but there are other types of HRT like Femoston (tablets) which are more body-identical than the patch you're on.

There is also a tablet from called Tridestra which is a 3-month cycle, so the progesterone is only 2 weeks out of 12.

Also, many younger women are prescribed the oral contraceptive pill as HRT and some are more body-identical, like Qlaira and Zoely.

I got referred to the gynae as local clinics wouldn't fit it.(Unless you can get nurse to say it's for contraception) Mirena worked for me - a steady dose means I don't get those suicidal dips any more. I

The progesterone in the patches is not body identical which can cause worse symptoms and/or you have progesterone intolerance. Mirena is a good suggestion as although it's also synthetic the dosage is much lower and directly delivered to your uterus. However you could raise your symptoms with your gp and ask to swap to oestrogen only patches with oral micronised body identical progesterone. If the symptoms persist you could try switching to then inserting the capsules vaginally.

I’m getting the Mirena fitted next month to have progesterone delivered that way - I’d definitely speak to your GP to see if this is an option. I can’t wait, I also fantasise about canals - but mine is wanting to throw other people in the as opposed to myself.

I took estrogen body identical gel and utrogestan capsules for progesterone, also body identical. My rages were so hideous, I caused permanent damage to family relationships for the two years I was on it.
Hrt healed my medical problem but left me in a terrible state .
Perhaps try the Mirena as suggested.