Apparently high levels of estrogen in the body can irritate the cells that produce insulin in your body, making you insulin resistant and blood sugar levels rise, leading to weight gain.
I thought it was the other way round!
Women on HRT have a lower risk/ level of diabetes and lower risk of visceral fat deposited around the tummy.
If it was down to high estrogen, then surely all young women would be fatter as they have the highest levels?
I dont think it's a case either that insulin resistance leads to weight gain. Isn't it the reverse? People who are overweight become insulin resistant, and one of the symptoms of diabetes is losing weight because the pancreas can't convert glucose to energy, so diabetics feel hungry all the time and they pee a lot as the body is trying to get rid of the excess glucose.
I think one reason for weight gain is starting on the wrong type and dose of HRT. A lot of women are put on a high dose, and continuous combined HRT- both hormones daily.
Progestogens are often the culprit as we all know that women retain more fluid in the 2nd half of a menstrual cycle (PMS) .
Some menopause specialists will suggest starting on estrogen-only for several weeks to get the dose right, then introduce progestogen after 3 months. (This is what I did.)
The problem is that many GPs don't know these variations and dish out a 'one-size fits no one' HRT.