Provera dose?

[Movinghouseatlast]

I have been swapped from Utrogestan to Provera to try to control post menopausal bleeding. Even a 300mg dose of Utrogestan didn't stop it.

I have been prescribed 2.5mg daily of Provera, but I don't think this is the right dose. I have started bleeding again today, only 6 days after it stopped.

Does anyone know what the correct dose should be please? My doctor had never prescribed it before.

I have had a scan for the bleeding and there are no issues.

Thanks.

have been prescribed 2.5mg daily of Provera, but I don't think this is the right dose.

Why do you think it's not right?

I can't help, sorry, but maybe google the drug and read the patient leaflet/ prescribing info online? Might be there.

Yes, I have done that obviously. The leaflet makes no mention of its use in HRT and google doesn't have any mention of a dose.

I just thought someone else may have had it prescribed which is why I asked

www.drugs.com/dosage/provera.html

PROVERA tablets may be given in dosages of 5 or 10 mg daily for 12 to 14 consecutive days per month, in postmenopausal women receiving daily 0.625 mg conjugated estrogens, either beginning on the 1st day of the cycle or the 16th day of the cycle.
Patients should be started at the lowest dose
The lowest effective dose of PROVERA has not been determined.

From Menopause Matters website

www.menopausematters.co.uk/to_progestogens.php

PROVERA -
also available as Climanor (5mg tabs)
MPA 10 mgs daily for 14 days per 28 days

Yes, I have read that but I am post menopausal and the label says 2.5 mg daily. I think I'm supposed to use progesterone daily. Hence I wanted to hear what others have been prescribed.

I don't have a cycle, I'm 56.

I take provera continuously 10mg to stop my periods. I saw a private gynaecologist who prescribed oestrogen gel in addition to the provera as HRT. She said 10mg was much higher that the normal HRT dose which I think was 2.5mg. I am sure you can find more information online.

I have 10 mg with oestrogen vaginal tablet and evomera 50mg patch. Private GP too

I am actually prescribed 20mg a day but advised to take the lowest dose I can. I also have a coil fitted which is meant to be a better way of getting the right amount of progesterone but unfortunately didn't help me.

Yeah I can't have a coil

The dose of Provera will depend on how much oestrogen you’re taking, so if you have a look at the attached 2.5mg would be prescribed with 25mg patch/1 pump Oestrogel, 5mg with 50mg patch/2 pumps gel and 10mg for 100mg patch/4 pumps gel. If you’re on a higher dose of oestrogen you should double check the Provera dose with your GP or pharmacist.

www.menopausematters.co.uk/postmeno.php

If you click on the post menopause option on the menu, it's got it all there.

@Movinghouseatlast You've not said what dose of estrogen you are using and what type- is it gel, or a patch? Is it a high dose?

I am wondering why your GP hasn't suggested a tablet form for combined continuous?

There are plenty to choose from, as well as some patches.

If you look at the previous link I left you. the Menopause Matters/post meno one, there are tablets that contain MPA (MPA is Medroxyprogesterone acetate , brand name is Provera) .

Or you could use patches or tablets with Norethisterone (which is stronger than Utrogestan.)

I'm on Evorel 75.

The GP literally didn't know what to prescribe, she looked it up in a book then left the pharmacist to decide the dose as she didn't write it on the prescription.

She did suggest tablets but I believe the breast cancer risk is much higher from what I've read.

I think I might just give up to be honest and see if I can live with the symptoms. I am bleeding 3 weeks out of 4, nobody seems to know what to do to help me. There is no menopause clinic where I am, it got its funding removed. I might go private I guess.

Just to make a couple of points that might help you @Movinghouseatlast

MPA (which is Provera, as a separate tablet) is shown in the research to have the highest risk of breast cancer.

There is a 'league table' of risk, with MPA being the highest, then Norethisterone, then dydrogesterone (only available in Femoston) and micronised progesterone being the lowest.

Whether you use tablets or any other type doesn't affect breasts. The only difference with tablets is they have a slightly higher risk of stroke/ blood clots as the estrogen goes through the liver and affects blood fats.

Have you thought about reducing the dose of your patch? You might get on ok with a 37 or 50mcg patch. Bleeding is usually linked to the amount of estrogen used. 75 is classed as a high dose.

There are loads of 'easier' options rather than combining a patch with Provera.

All the combined/continuous patches, and all the tablets.

Maybe you can do your own research, and think about what you prefer, and go back and discuss?

Whether you use tablets or any other type doesn't affect breasts.

Just t o clarify my own post!

It's the type of progestogen that is related to breast cancer, not estrogen.

I have already done combined patches and a lower dose of oestrogen. Nothing stops it.

I’m on Provera 10mg daily and Evorel 100 patch. I was bleeding frequently on Utrogestan so GP changed to Provera and bleeding has stopped. Been on it for around four months now.

Thanks! Looks like it should be 10mg then. I will have to show her the dosage.

I will have to pay another prescription charge because I' be been prescribed the wrong dose, which I know isn't the end of the world but it's the fourth time they haven't given me the correct prescription!

I'm on 200mg a day for cancer. Oncologist says highest he's prescribed is 600mg per day!

So your well within the safe limits so I would increase if you need to