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Menopause

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Activelle; estradiol 0.5mg and norethisterone acetate 0.1 mg tablets

11 replies

CourtneeLuv · 10/11/2022 16:36

Thoughts/opinions on these please?

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JinglingXmasbells · 10/11/2022 18:02

why? :)

CourtneeLuv · 10/11/2022 21:58

This is what I've been prescribed and I'd like onions on whether it's decent or not.

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CourtneeLuv · 10/11/2022 21:59

Opinions, not onions 😂

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JinglingXmasbells · 11/11/2022 13:51

I don't know anyone on less than 1mgs of estrogen. I'd never even heard of it and it's not on this list. www.menopausematters.co.uk/postmeno.php

The only equivalent is the ultra low dose of Femoston which also (as it happens) has a safer form of progesterone (breast cancer risk.)

The lowest dose of patch is 25mcgs ( roughly 0.5mgs estrogen) and that's about the very lowest and rarely used.

Are you in the UK?

chocolatenutcase · 11/11/2022 13:56

The current thinking is to have HRT delivered transdermally, ie through the skin. This can be as gel or patches. The aim is to reduce (in many cases) minimal risks of HRT.
So if this is your first prescription I'd say go back and discuss transdermal HRT. You might have chosen tablets by choice after discussion of pros and cons but it's a tiny dose of oestrogen and you may need more which would mean going back to get higher dose tablets.
This is the best website for information

www.balance-menopause.com/

CourtneeLuv · 11/11/2022 15:37

No I'm not in the UK.

I have to go back before the end of this pack for a review.

I don't have any major symptoms, just a bit of dryness and loss of libido. They are prescribing for bones/heart etc benefits.

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JinglingXmasbells · 11/11/2022 16:26

It's really difficult to help when you aren't in the UK, as all countries do different things with HRT.

France, for example, is very keen on Oestrogel and Utrogestan and was prescribing long before the UK (well, GPs, at any rate.)

Also in the UK HRT is not licensed for prevention of bone loss or heart disease in women with a normal menopause age.

It can be prescribed for prevention of bone loss & heart health for early and prem meno ( or for women with a risk of osteoporosis .)

Here, the usual treatment for dry vagina etc is topical vaginal estrogen. Libido- hmmm- not many women get it just for that.

As a PP says, the trend here is for transdermal HRT to reduce the risks of blood clots, and natural micronised progesterone to keep the breast cancer risks as low as possible.

So- that's a long way of saying that in the UK your treatment and choice of HRT would not be that tablet form, or even HRT at all.

JinglingXmasbells · 11/11/2022 16:27

or even HRT at all Unless you are having an early menopause.

CourtneeLuv · 11/11/2022 17:47

I'm 41 and my periods started going awry at about 38. Only just being picked up for what it is now. POF/POI. At the end of Jan/beginning of Feb I'll be 12m period free. The gynaecologist recommended hrt til normal menopause age.

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JinglingXmasbells · 11/11/2022 17:56

which country are you in?

As PP says, transdermal is now considered safest not tablets. Tablets are now a bit dated.

It's great you have been picked up as needing hrt for POI but the dose is minute.
Usually, younger women need more , not less.

Even high dose estrogen doesn't go anywhere near what we have naturally, so I'm puzzled by this dose.

As I said, it's not available anyway in the UK.

I'm not sure if the dose is high enough to prevent bone loss. I have been advised to use at least 1.5 mgs and on the link I left, those with an * are also prescribed to prevent osteoporosis, so check out the doses- most are at least 1mg.

CourtneeLuv · 11/11/2022 19:01

Maybe the gp is going to increase it next time, I have to go back just before these run out.

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