Hello all, I'm 3 weeks into Estradot 50mcg and on the day I change my patch, I feel incredibly wired with jittery/nervous energy, no appetite and a kind of feeling I can only describe as tension in my face/jaw. It's like being on some kind of weird 'upper', lasts all day and is really exhausting. Do you reckon I need to go down to 25mcg and work my way up? Has anyone else experienced this? I'd be so grateful for any advice as these unpleasant 'highs' are really exhausting.