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Menopause

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Utrogestan - side effects, including bleeding

3 replies

Clarice99 · 04/07/2021 10:15

I'm post menopausal and 6 months ago I was prescribed Oestrogel 3 pumps per day and oral Utrogestan 1 x 100mg for 25 days (with a 3 day break).

Prior to this regime, I was on Femoston Conti.

I really wanted to feel a positive difference on the new regime, but my mood became lower, I felt more anxious, was sleeping far too much, had no energy at all and could not get through the day without napping.

I recently had a review appointment with a menopause specialist nurse (she originally prescribed the above regime) and she advised to use Utrogestan vaginally, 100mg capsule every other night (half the dose I was on orally).

While I feel better in myself, I'm not sleeping as much, not napping during the day and my mood seems a bit brighter, after starting the above regime, I had some spotting a few days after starting the vaginal Utrogestan, which after 2 days, became a bit heavier.

So as not to 'drip feed', earlier this year I had a scan and a hysteroscopy and was given the all clear.

I reported the bleeding to my GP and I had an examination at the GP surgery 3 days ago. I was told that my vagina and cervix look fine and as the bleeding stopped after 4 days and in view of the recent 'all clear' from the hysteroscopy, the bleed was put down to a change in the delivery of Utrogestan. My GP did offer to refer me again for another scan, but that would mean I'd have to come off HRT again for 3 months prior to being referred and in view of the change in the regime, I do think the bleed/spotting is due to this.

The spotting started again yesterday and I'm wondering if it could be due to the fact that I'm only on half the dose of Utrogestan now than I was when taking it orally (and I had no bleeding/spotting then).

Also, I suffer from constipation, it's a life long thing, but it's worse now I'm using Utrogestan vaginally.

I'm wondering if I'm in the minority of women who are not suited to Utrogestan and if anyone can suggest a suitable alternative. I don't really want a Mirena coil as I had a coil fitted for contraception in my early 20's and it was such a horrible experience, I can still remember bit of it now!

Sorry for the long post.

OP posts:
Spodge · 05/07/2021 19:14

I don't understand why the dose was halved before trying the full dose vaginally to see if that was better. Unless the dose is thought to be "stronger" if you take it vaginally?

I take Utrogestan vaginally and take one 100mg every day (no break at all). That said, I've had no end of spotting recently. Since having my AZ jab, though, so not sure if that has affected things. I've only been on the continuous regime for under 3 months so things might just be settling down.

Clarice99 · 05/07/2021 19:58

I did query the 'half dose' and was told it's due to delivery method, 100mg for days 1 to 25 orally (with a 3 day break) or 100mg every other day vaginally.

Spotting/bleeding has been going on for about 3 weeks. I had the 2nd AZ vaccine about 3 weeks ago so it could be connected (?)

Following an appointment with my GP today, the HRT has been stopped for 2 weeks as the constipation has become so bad and I don't think this regime is right for me.

I feel crap.

OP posts:
Spodge · 07/07/2021 19:14

Sorry you feel crap. Hope you can find a regime that suits.

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