I’m 48 this year and I have been taking Evorel Sequi patches for approx. 18 months. It works well, my main issues were low mood and irritability. Recently however I have started to experience irritability (understatement) again and I wonder if at my next review appointment I should ask my GP to up my dosage from 50 mg to 75mg. I am not sure if I should be on a higher dose as I am peri or lower because I am peri, for once Google has let me down.