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Increasing Sandrena dose

5 replies

AnastasiaaBeaverhousen · 07/08/2018 13:35

Wondering if anyone can offer any advice here. I’m 36 with POF with early peri-menopause and have been on low dose HRT (1 mil sandrena gel daily and utrogestan 100 for 12 days of the month) since April. Before going on HRT my main problem was constant low mood and irritability, not really any hot flashes or other issues, although my periods did vanish suddenly in the three months before I started taking it (like turning off a tap!) but to be honest that didn’t bother me.

I did feel a lot better mood wise very quickly, but the last couple of months have been very stressful for general life reasons (house move, work stress, etc), so I didn’t think much of my low mood and irritability slowly coming back. I just ascribed it to external pressures. However I’ve now been on a much needed holiday for two weeks and have only continued to feel more and more down to the point I am now almost permanently on the verge of tears if not crying, feeling very anxious and generally feeling quite worried about my mental state. My libido has also largely vanished, which is something that never happens when I’m on holidays. I thought this holiday would make me feel amazing but I just feel worse and worse.

I’m out of the country for another two weeks and am not due to see my specialist again until September. Do you think it could be worth my upping my sandrena dose to 2 mil per day to see if that helps in the meantime? I feel so wretched and none of the things i usually do to lift my mood are helping. But I’m not sure if it’s ok to up the dose without dr’s advice or while mid-cycle as I am now. No point emailing or calling the clinic they would take ~ 2 weeks to get back to me anyway!

Any advice welcome! TIA.

OP posts:
QueenoftheNights · 07/08/2018 14:26

1mg is a very low dose for anyone with POI.
I use more than that in my 60s (1.5mgs and any time I've reduced, I feel the symptoms coming back.)

Yes, increase the dose. No brainer!

Emerald13 · 07/08/2018 19:49

I am 42 and on 2 mg and sometimes find it too low for me but my gyn doesn’t agree with my suggestion for BCPs. You absolutely need a higher dose or BCPs not only for your mood or your libido but for your overall health.

AnastasiaaBeaverhousen · 07/08/2018 20:19

Thanks both, I will go ahead and double my dose. Can I ask, do you take your 2mg at the same time or half in the morning and half in the evening?

OP posts:
Emerald13 · 07/08/2018 20:29

I take a pill that contains 2mg at night, before going to bed.

Losingthewill8 · 08/01/2019 11:03

AnastasiaaBeaverhousen It may be too late for you, I just found this thread, but I had to come off utrogestan! It really brought me down.

I am on Sandrena gel 1mg sachet, nothisterone for progesterone at night 1 tablet and a bit of testosterone.

How and what time of day did you apply your gel? Mine takes forever to dry in the morning, it a complete pain!

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