lljkk I think we are discussing 2 different issues. I thought originally you were saying that when women came off HRT their symptoms were worse- implying that HRT made them worse.
Yes, of course, many women's symptoms come back when they stop HRT. There are two points here: is it worth improving quality of life for some time (with HRT) than not improving it at all. And is there any need to come off it? Many consultants now- and this is discussed in a recent statement by the British Menopause Society ( on their website) are happy for women to stay on HRT indefinitely as long as there are no increased risks that outweigh the benefits she's getting. it's erroneous to think it always has to be stopped. Some GPs are doing this but they are not up to date.
If a woman chooses to come off it then yes, symptoms may return and then there may be other things like weak phytoestrogens that may help some women. I know someone of 74 who took HRT for 20 years came off it for 6 months, felt dreadful, couldn't function, and is now back on it.
When women come off it they have to do so gradually over 6 months, and at the same time try supplements which may help.
My mum is late 80s and has never got rid of her hot flushes - I was told by a consultant that some women don't - about 10-20%.
It's all a personal choice and there is no one-size fits all.
Margo yes, I ADs provide benefits for hot flushes. Menopause Matters info ( below) they are used primarily with women who have had breast cancer. They can also cause some of the problems women have with menopause already- insomnia, etc.
SSRI DRUGS (Selective Serotonin Reuptake Inhibitors). This is a class of anti-depressant drugs which seem to work on the "thermostat" receptor as well as neurotransmitters. Examples are Venlafaxine, Fluoxetine, and Paroxetine. They have been studied and widely used effectively for reducing flushes in women who have had breast cancer [Ref 11 and Ref 28] . Care should be taken however, if Tamoxifen is being taken as part of the treatment for breast cancer since studies have shown that some SSRIs may interfere with the action of Tamoxifen. Venlafaxine seems to be less likely to have this effect and so is the preferred option in this situation. The dose of SSRIs can be started low and increased gradually to minimize side effects. A greater reduction in hot flushes is seen at higher doses but the side effects such as nausea, dizziness, problems with sleeping, agitation and confusion may be worse.