I live close to Manchester, which I find a great city - very vibrant and very friendly people, though the weather can be very drab for long periods through the winter, which could get you down (it's famous for being quite drizzly).
I'd say that Manchester has become England's second city, after London (though some would disagree). The transport links are excellent, road, rail and air (you can fly directly to Manchester from most parts of the world and the airport is pretty close to the city centre, relatively speaking). The city is also served by an excellent network of buses and trams.
The shops are great - some smaller versions of the large shop you might find in London, and the city centre has a real buzz to it. Great nightlife, smart hotels.
Nearby you can get to the peak district very quickly for some real open space, or to the Lake District wihin about 1.5 hours for the scenery (and the crowds, in summer). There's not much in the way of coastline if that's what you are used to. The nearest coast is Lancashire (Blackpool-ish) but it's not pretty (sand dunes at Formby ok). You can easily get to other places such as North Wales (Snowdonia National Park) and to cities such as Liverpool and Leeds.
And then you have Cheshire, Lancashire and Yorkshire on your doorstep for a taste of rural british life.
If you are here for 12 months I'd go for renting fully furnished. You can buy cheap at Ikea, but the cost of living in the UK is enormous, so furniture prices are correspondingly high. It should be relatively easy to find a furnished house.
Cars are expensive, but running them is the real expense. You need to be aware of the extras like road tax, insurance, MOT etc. Fuel is expensive so you might consider a diesel engine for greater economy.
If you decide on Manchester, I can give you lots more help and specific information. Perhaps your friends/family could send you a copy of "City Life" and the Manchester Evening News, as this would give you a better idea. You need more information on the specific neighbourhoods to make a choice about houses and schools.
Good luck and CAT me if you need anything