Ovulation before egg collection

[Merano]

I had my egg collection today at Create St Paul’s and am devastated as the doctor told me that I had ovulated from three follicles prior to the operation. They had booked my egg collection in the afternoon, much later than on my previous cycles and I am now left with the feeling that they have mismanaged my medication and the timing of my retrieval. Has anyone else had this happen? It feels like such a waste.

Yes it can happen , although it's not common.
I've ovulated twice prior to egg collection despite being on ovitrelle to prevent premature ovulation.
On my last cycle I had several empty follicles with no eggs which resulted in collecting only 3 eggs, which we froze.
I then found out i was pregnant naturally , therefore I absolutely ovulated an egg prior to collection

So sorry to hear that. I’ve always been so terrified of that happening. I only usually get around 3 eggs if I’m lucky so it would be disastrous. How many eggs did you have collected?

I’d say the time in the day doesn’t matter as much as how long after trigger it was scheduled.

im actually getting treated at the same place at the moment.

Yes it hadn’t even crossed my mind honestly so it has come as a bit of a shock. I had four good sized follies at my last scan and it looks like the clinic have allowed three of these to get so large that I ovulated early. I feel so disappointed as this was looking like a strong round for me (at 41 with low amh). The operation was at the correct time folllowing the trigger shot. The doctor managed to retrieve three eggs, I will hear tomorrow about how many have fertilised. In previous cycles I have had a high failure rate on embryos after day 3 so I am not feeling very hopeful at the moment. Sad. How has your experience been with Create?

Hi I am so sorry it's a horrible feeling it happened to me recently too. My amh is high but because of various risk factors I was put on super low dose stims. But they still expected around 15 eggs. Ended up getting half so I was absolutely devastated. Especially as this was our only shot at this and I am somewhat medico phobic. I had definitely prematurely ovulated eggs as the bigger follicles were no longer there on EC day. They put me on Certrotide to stop premature ovulation and I also had a blood test day after trigger to check lh levels which were low. So we think between blood test day and collection day I must've ovulated pretty quickly. Unfortunately I think my body just got a way round the cetrotide. Timing was spot on so definitely wasn't that. They seemed to have done all they could in my case. If you do another ec definitely make sure there's no time delays and have scans, blood tests between trigger day and ec. Also I don't know if you can but I'd ask if I could take cetrotide right till ec day xx

Yes I have had this also. And then ended up with a complete fertilisation failure . I complained to my doctor and he put me on a different protocol with a better outcome . I knew in my mind that we should have not carried on with the egg retrieval but I trusted my doctor and he got it wrong. I understand mistakes happen but I wasnt happen and then I got a discount on my next cycle.

Ah god sorry @Merano. I mean still having 3 eggs isn’t hopeless but having low amh makes every egg precious. I think it does unfortunately just happen sometimes but if it had happened to me I’d feel sick to my stomach. Just like you I have poor blast conversion, male factor and my age. We get perfect day threes that fail to continue. Our last round we opted for natural modified to just try something else before moving on to donor conception. We got a 4ab blast. Considering we’ve not made a blast out of the last two rounds (9 eggs total) I’m pleased/hopeful but also confused. Oh and at egg collection I was told about the much higher chance of ovulating before collection when doing natural modified. I’m glad I didn’t know before hand.

@Needamiracle12 Yes I agree, with more monitoring this could have been avoided. They didn't ask me to come for a blood test the day between (Tuesday), despite having four follicles well over the line on Monday (three of which were lost). EC was on Wednesday. My previous egg collections from cycle 1 and cycle 2 had been at 10:15am & 8:30am. This one was booked for 12:45pm despite my strong response on this cycle (and confusingly having always been told that EC are always in the morning). They told me they had other patients booked earlier despite me pushing for a morning EC. I believe they have breached their duty of care in this instance as they have clearly allowed the clinic to become overbooked to the detriment of what is best for the patient. There was no reason for them to change the timings from my previous cycles.

@sisterdaughter I'm glad you got a blast, I really hope that one sticks! It is so tough to have a lot of hope at day 3 and then to lose them, the rollercoaster of emotion is wearing. We lost all ours after day 3 on cycle 1 so the clinic advised picsi after that. I asked if my partner needs to do a DNA fragmentation test, but the Doctor said that it isnt necessary if we are using picsi. I still find that odd. Here I am being injected with hormones and going through operations, surely if there is a way of monitoring sperm health with a view to improving it, it should be done.

Hey, just wanted to add this happened to me too. Ovulated early and all the follicles had emptied. I was heartbroken as there was around 20. The only thing they have changed for this cycle is the collection time will be one hour earlier than the previous retrieval which honestly doesn't feel like enough to me 😢 I have heard it's rare and may not even happen early this time but it feels like very little support has been offered to help avoid it happening again!

@Merano i so agree with this. I was met with resistance to fragmentation testing too, fair enough he said no point, but we weren’t offered picsi and it was only my research that told me about male factor after day three. We were at the end of trying with our own gametes as it’s been so long (not sure if I said above, 4+ years) and we just want to start our family (and stop getting our hearts broken). If we do have another go (given the quality embryo) I’d ask for picsi for sure.

but anyway, I’d 100% push for some kind of compensation if it was the time of the collection that affected things. Not that money would take the anger away… eggs are so precious.

@sisterdaughter Same, I raised DNA frag test having spent hours reading into embryo failure after day 3. I have found another clinic that do it but it would have been better all under the same one. I wonder why they haven't recommended picsi as you seem to have a similar outcome to mine?
Yes every egg is so so precious 💗
The clinic retrieved three on my last cycle so to be so negligent to lose three on this cycle is heartbreaking.
Have you had your embryo transfer yet? We have one Day5 from the previous cycle but want to send it for genetic testing. Wishing you all the best Xx

@21RsMama I am so sorry to hear you went through it too. Just devastating. Worth pushing for an additional appointment and blood test the day before ec? But yes, you would think that the clinic would offer that to prevent it happening again..

Thanks @Merano :) our first blast we have made with create has implanted, so at least I know there’s no real issue with that part. Given my history, I’m not allowing myself to look ahead at all, just a day at a time, and enjoying waking up with good news every day. Long may it continue.

I really don’t understand why they didn’t offer us picsi? I really have a feeling that fertility treatment is skewed in favour of males—right from the start before even getting amh tested, it was presumed it was my egg quality and I was encouraged to think about donor egg. I always listened thinking it must be true, but then when I point out our beautiful day 3s that fail to develop, and his very poor morphology, only then do they concede that the male factor is playing a role.

I hope your wee embryos are developing nicely x

@sisterdaughter oh that is such good news! Wishing you all the best😊
Yes it certainly seems that they'd rather put the woman through all of the medication and invasive treatments before even looking into male factor. I also presumed it was my egg quality but after trying for so long add with the same failure pattern I begun to question it.
This round typically all 3 eggs made it to day 3 but they haven't reached blastocyst at day 5 (today). I tried to not get my hopes up but it's crushing every time. I will wait to hear if any make it tomorrow.

Oh pal, that’s exactly what was happening to me. My last round (which so far is a progressing pink line) was natural modified, just one egg and obvs much better results. But I still question if it was truly my egg or a lucky sperm pick, or both qualities being improved. Apparently a high quality egg can correct issues with mail factor…

lol… male not mail.

anyway, absolute best of luck that they all continue and are just slow to reach blast ♥️