2 FETs 2 miscarriages

[waitingforourmiracle]

Hey all,
Wondering if anyone has experienced something similar and if there is anything I can do different for my next embryo transfer?
First cycle I 1 embryo graded 4CC and had a frozen transfer, MMC discovered at my clinic scan at 7 weeks
Second cycle and second frozen transfer in July was a 5AA so was more hopeful due to grading but I bled at 4w6d and miscarriage was confirmed by bloods a few days later so I stopped my meds on Friday and I'm now bleeding.
It took me a full year to prepare myself for another round of IVF and I'm already dreading the thought of another transfer, the thought of the same thing happening again is making me not want to go ahead 😫
We're very lucky that this round we got 10 embryos frozen but my only thought now is the whole lot must be bad embryos if this first one didn't work and they will all end in MC, I know that isn't necessarily the case but can't shake that thought.
I just feel drained from it, I know people have been through a lot more than this but how do people deal with it and did anything change for a 3rd transfer?

I’m sorry you’ve had to go through all of that! How are you feeling?

we’ve had something similar with a miscarriage happening closer to 11 weeks after there being no heart beat at the 9 week scan at the clinic but continuing to have rising betas. Followed by another chemical pregnancy which thankfully didn’t last long.
in a way I love but also dread seeing the second line as it brings so much uncertainty and in most cases for us an unfortunate ending. We’ve had transfers and thankfully one live birth in 2024. The only thing that I can say it’s worth to keep going if you can.
my consultant has put me on baby aspirin, blood thinners and steroids to hopefully help but TBH unless you know what is causing the miscarriage (we didn’t test but had really good embryos) I think they just give you standard meds to try and prevent it. Might be good to do further investigations to see if something in particular is causing it? Have you tested the embryos? Do you think this is an option as you have quite a few?
we don’t make that many so had decided not to test them which I kind of wish we still did.

Thank you for your reply, if I'm honest I'm a mess at the minute! It's been a tough week.

I'm sorry you also went through losses, it all seems so unfair. We have a follow up on the 28th August so I'll ask the question with them obviously I just wanted to know if anyone changed anything! We asked about testing but decided against it this round but once we found out we had 10 it would of added an extra 5K so it wouldn't of been possible anyway after just paying 12k for treatment! Another thing that seems so unfair, the prices!! It's all just one big rollercoaster I don't want to be on!! X

I know what you mean! We’ve self funded all the cycles and this is our fifth so it does add up and testing is so expensive.
I know people look at killer cells and other things too I think so worth researching and asking the clinic. But I also think that a lot of the time it’s just the embryos, even though they are of good quality and sometimes there’s nothing that can be done other than going again. Which I know is extremely tough! But the great news is that you have loads of Frosties!! Congrats 10 is an absolutely amazing number!
when are you thinking of doing FET? Could you consider an anti inflammatory diet perhaps as that could also potentially help.

the best of luck with everything x

Wow 5 rounds I couldn't even imagine! I'm so happy you got there in the end!
I know we have been really lucky, our first round we just had the 1 embryo so 10 is still hard to believe! As soon as I can really, as soon as the clinic says we're able I think I need to wait a full cycle before I can go again, my cycles are very irregular though so that's another fun factor! 🙄X

So sorry to read

Would something like alice / emma test be gd ?

Have u done any tests on the environment / uterus?

Also - age may be a factor (?) - dunno your age - maybe they were chromosonally abnormal

@waitingforourmiracle I remember you from the July 25 Fet group - I was on it until my transfer was cancelled..I'm so sorry to hear of your loss. I understand the physical and mental exhaustion having had a few rounds of IVF and now stuck in what feels like perpetual limbo to even get to FET...as others have said, it's great you have 10 embryos. Statistically, the one you need is in there but right now, I hope you can retreat for a bit and rest up and then try again. I also have irregular periods making this process more complex.. I'll be taking decapeptyl in Sept for FET hopefully so we may end up on similar time lines. Take care.

@worldwidetravel2017 I haven't had any testing no, I will ask at my consultation about these, I'm 30 so age I'd hope wouldn't be a factor

@Sara237 Yes I remember you too, how are you doing? I know I'm thinking on emotion but at the minute I just can't see any of them working and I can't seem to shift that! Is decapeptyl to help regulate your cycle? I've not heard of that before x

You may have pcos - esp with irregular cycles

@worldwidetravel2017 yes sorry I didn't mention that, I do have PCOS x

I would ask the clinic for the pill to help induce the bleed ahead of your FET. I have irregular periods and have done this to help plan the rounds better.

@waitingforourmiracle PCOS can sometimes cause more challenges for egg/embryo quality and retention. Check your fasting glucose and insulin to see whether you need to adjust diet to lower inflammation/ regulate hormonal and metabolic issues.

Are u on metformin?
Metformin reduces miscarriage risk - its how im 10 weeks preg nearly.
That & pgta testing.

Pcos effects qual of eggs - which may link to miscarriage

@waitingforourmiracle yes decapeptyl is what the clinic have suggested to shut down my ovaries as they are unable to monitor me properly due to being abroad and I ovulate oddly - on day 4 sometimes, yet low progesterone, though have collapsed corpus luteum? So they're unclear what's going on and advise me to just have this injection to shut it all down! Like you, I have zero confidence in any of this working. It feels momentous and I'm hemorrhaging money that I really can't afford; I mean if it actually works I've no idea how I'd afford maternity leave! But on it goes, the endless scans and pills and waiting, crying etc etc. I know you know. Age is on your side. Oh to be 30 again! I'm 48! Age is not on my side!

I dont know if youd be open to donor eggs but my friends your age & just had her ivf baby

@worldwidetravel2017 Yes, we have 5 x day 5 embryos from donor eggs, I wouldn't attempt own eggs at my age! I just can't seem to get to the point of actually having the FET! Thanks. That's great about your friend.

Sending u all the luck

@Sara237 I'll ask about that, I tried nortethisterone on my cycle before my transfer but I didn't start it until about day 35 and it still took another 10 days to bleed! I think realistically my next transfer is going to be October which feels like forever away! Best of luck and please keep me updated with your next cycle xx