Is IVF even for me when I get pregnant but have recurrent misscarriges ?

[Ilovebees]

I just want to get it off my chest because I feel so hopeless ! I started ivf after 5 natural misscarriges between 5-6 weeks . All happened in early 20’s. I started ivf at age 29 and have had another 2 losses at 5-6 weeks after ivf trasfer ,and just lost my natural pregnancy again this week at 5-6 weeks , so 8 losses so far and no children to show for it . Every test on nhs came back good . Chromosome testing , Blood clotting , sperm tests , thyroid , ect . I was put on blood thinners and aspirin and progesterone and still lost 2 . My specialist thinks it’s egg quality as there is no other reason on blood tests that say something is wrong . Been told I have very mild pcos but did not have it in my early 20’s but still lost my pregnancy’s . I just don’t know if ivf is the right thing for me as I can get pregnant but just can’t stay pregnant . Any advice greatly appreaciated or what else could I try :)

So sorry for all your losses ❤️ are you genetic testing your embryos? This is now listed as green on HFEA website for recurrent miscarriage. It might mean you are less likely to miscarry them if genetically normal.

I was also going to be getting a hysteroscope if I miscarry again - just to check for any uterine absnormalities. Might be worth getting one of these if not had it already?

I suppose if you keep trying naturally it sounds like you fall pregnant easily but you might end up having more losses 😭 maybe it is a numbers game just getting the right embryo? Still pretty hard to go through this though.

It’s so hard to know if it’s the egg quality or the environment. Do you have people supporting you at the moment through this time? How are you doing? xxx

I'm really sorry to hear of 8 losses. That's awful and, to put it bluntly, not normal. Google Dr Shehata - he specialises in recurrent miscarriage. He is expensive (£3k for tests and then treatment on top) but he may find something. Or he might not.

Do immunology testing. Ask your Dr to refer you to Dr gorgy or Dr shehata. There's fertilysis testing too. Drs like to blame egg quality but I think if your getting pregnant that many times it's unlikely its the egg quality.

Also try and get doxycycline for you and your partner and take for 2 weeks. You can get it on superdrug pharmacy

@Ellenn hey , no we haven’t done genetic testing on embryos as my clicking doesn’t do that yet . And I have had 2 hysteroscopy already , I have arcute uterus , mild heart shape but my consultant says this has nothing to do with losses , I had a small polyp removed but didn’t improve my chances and still had 2 losses after . And I don’t have any support other than my partner , this has been going on for years now , but ivf only 2 years , but I don’t want to tell anyone about my troubles as I feel embarresed that my body can’t do what everyone else’s body can so I bottle my feeling inside xxx thank you for replying to me xx

@2024sun hey thanks for the reply , I have tried the doxycycline few years ago for 2 weeks , I ordered it online , but seems like it didn’t help , my partner didn’t take it though just me . And I have been thinking about dr sheata and the immune side of things , so I asked my consultant to let me try steroids predionsole 20mg next time I go for ivf and he agreed , but he doesn’t belive in them though so I had to push for it , so I guess it’s a shot in the dark but maybe it will help me ? If not then I will seek help from fr sheata as I know the nk cells can be high or low and if it’s low then I need different treatment which I’m not sure what it is xx

COQ10 helps with egg quality. Take a look at the book 'it starts with the egg' it has a lot of advice and recommendations for supplements. I am 40 and mine was egg quality for my second child. I'm 34 weeks now after following the book - I did the advanced plan - upped it after my first round wasn't very good at all. Best of luck OP. I had 3 MCs and 2 failed transfers before this one decided to stick around.x

I also did fertility accupuncture x

You're so young so unlikely is egg quality. Have they tested you for endometritis?

I think you have immune issues, sometimes Prednisone alone is not enough, I'm taking a combination of 3 immune medicines (to lower my immune system) plus blood thinners. It's best that you see a Reproductive Immunologist like others suggested. You don't have to do IVF, they can work with you for natural pregnancies.

Good luck!

Ask to be refer to Coventry & Warwickshire hospital. Professor Quenby and Processor Brosens both have specialty within recurrent miscarriage and can help.
I had 4 early pregnancy losses (6 weeks) I went through tests and then was put on steroids my daughter was born in July 22. I also took lots of different vitamins along the side recommended by a dietician.
I had another miscarriage in December and went through the new test that Professor Brosens worked on and I was diagnosed with low NK cells and low and a low immune system for implantation. This was not diagnosed previously. I have now a medical plan to try and have another successful pregnancy. Also price of the test is very very reasonable

This! I’ve had 15 losses at 5-6 weeks. I’m under Prof Shehata as tested positive for overactive immune system. Everything else is normal, including Alice/Emma/ERA. We also know we can make genetically normal embryos via PGTA embryo genetic testing.

My Dr said that at this many losses, it is far more than just egg quality. Because even at my older age, 1 in 3 eggs should be genetically normal, it is statistically not possible for all of the 15 eggs in those pregnancies to be abnormal. If it was 2,3 maybe yes. And he thinks it is my immune system. First FET soon so will let you know…

My losses were all natural and we conceive easily too.

I recently had dental work for gum disease and read that it can be a cause of miscarriage. General inflammation in the body. Probably quite low down on the list of possible causes but something that could maybe be easily checked on the off chance.

Very best of luck.