Hi there.
Mind me asking you if you have previous experience of MC?
There's a lot of mixed confusing information out there, but I'll tell you what I know based on my direct experience.
First of all, there seem to be at least one good quality study showing that taking 75mg Aspirin pre-conception (that is from 6 weeks prior) seems to reduce the risk of miscarriage in those who experienced it before - no difference in the general population however. This could be to a number of factor, blood thinning being one of them, but also reducing inflammation over time, which in turn can improve egg quality and risk of loss to chromosomal abnormalities as well as possibly reducing the risk of inflammatory/autoimmune reactions that can also sometimes be behind pregnancy loss.
I came across this information online after 3 back to back losses and decided to start taking daily off my own account so I'd reap the benefits for the next possible pregnancy.
I have seen spoken to 3 different specialists who all had very different views and prescribed a different use of it, I will outline their approach below. Meanwhile, I also learnt from a physician on another thread that aspirin is a COX2 inhibitor and COX2 is essential for implantation so to that extent, aspirin may prevent miscarriage, but also stop you from getting pregnant in the first place and is best taken once the pregnancy is fully establish to prevent issues such pre-clampsia.
Private IVF Clinic Consultant
- Told me to stop the 75mg aspirin I was taking off my own back immediately as that may stop me form ovulating in the first place
- Prescribed 75mg from the day of a PPT in a natural cycle alongside 2500iu Enoxaparin injections. I followed this and still had a 4th MC due to confirmed Chromosomal abnormality
- Prescribed 150mg + 5000iu Enoxaparin injections from 1dpo as part of FET protocol that ended in a chemical pregnancy - I didn't end up taking this as I was concerned about the impact on my stomach lining alongside enoxaparin injections I was also prescribed as part of the same protocol. When I questioned it, she said it was fine to forego the aspirin
NSH Recurrent Miscarriage Consultant
- Prescribed 150mg from the day of a PPT + 5000iu Enoxaparin injections
- in a natural cycle, I am yet to test this approach
Separate Private Fertility and Recurrent MC Clinis
- Told me to start taking 75mg Aspirin daily from the date of my 1st appointment and throughout all the time even during months when not trying at all.
- Explained that 75mg daily is way too little to have any impact on ovulation patterns and the first consultant was wrong in suggesting that
I had one superovulation cycle with the last clinic and did not fall pregnant at all, currently waiting OTD for my second cycle. As I believe in the pre-conception impact of taking it as well as pregnancy suppoer once established, but also have concerns about it impeding implantation because of the COX2 thing I learnt, this time around I decided to stop it form the day I was asked to trigger and planning to resume either on my OTD if negative or a few days later if positive to allow implantation to complete.
I hope you find some use in this information, but as I was saying there doesn't seem to be much agreement even within the medical community on it at the moment.