PGTA failure to pick up t21

[Claire12098]

Hi, I just wanted to share my experience of when PGTA can go wrong as I know this is something the clinics don’t share much about, especially when it comes to losses or problems beyond the first trimester.
I had two euploid embryos. One was a failed transfer, which although on the wrong side of the statistics (60-70%) it would take, I knew was a possibility.
However I’m completely blindsided and devastated by the second euploid transfer. Turns out at over 15 weeks pregnant that there is trisomy 21 (downs) in every cell. I have undergone weeks of testing and horrific waiting on this and my clinic don’t have an answer, simply saying they have never ever seen this happen before. So it might be completely rare but I was never warned about this possibility. Had I been I would have done the harmony test at 10 weeks instead of getting completely invested in the idea of this baby, especially after a normal 12 week scan.
Just really want to warn others as I think there is a lot of advertising that leads you to false comfort, even more so when you pass the 12 week mark. In fact I am even reading now cases of people who have lost babies to chromosomal disorders who are being told the solution to avoiding this is PGTA…
hope this doesn’t cause anxiety for those who have euploid embryos - chances are they will be ok but wanted to share this awful experience for others who are deciding on whether to invest in pgta or not.

@Claire12098 I am so so sorry to hear about your experience- it must have been an unimaginably hard experience for you.

I went through pgta but was told that pgta is not a failsafe process and sadly this was a possibility. They gave me a ton of information with all the pros and cons of pgta.

Did your clinic fully brief you on it?

Sending you lots of love x

Thank you, no I don’t think they fully briefed me but I did a lot of research on it before. They did say (and I was well aware anyway) that it’s not 100% guaranteed but this was much more around an embryo not implanting or maybe early miscarriage. They talked about reduced miscarriage risk. No mention at all that it could lead to issues later on, although I still haven’t found anything anywhere about other people with t21 after a euploid embryo transfer so maybe what is happening to me is just really really rare. They say they’ve never seen it happen before.

Regardless of rare or not rare. What a nightmare for you xx sending you lots of love

@CR7 thank you xx