Sorry this is going to be long! Just looking for some advice on next steps.
I have PCOS, DH has low motility and morphology. We are early 30s. We have one DD who is nearly 2 and was conceived on our first embryo transfer from our first ICSI cycle.
I always wanted a big family and so we have been trying for DC2 since DD turned 1. We had 3 decent quality blastocysts (all 4bb and above) in the freezer. One didn't survive the thaw, the other two both failed to implant.
We did a new round of ICSI late last year, lower doses as I was overstimulated first time and wanted to try a fresh transfer if possible as was worried the freezing had damaged the embryos (I know it's not really a thing but I was a bit fixated on it at the time). We only got 2 eggs - mad as I have loads of follicles - only one fertilised. I had fluid in my uterus so still had to freeze, froze at day 3. Transferred top quality 8 cell embryo in January, found out I was pregnant two weeks ago. I am now having a miscarriage at 6 weeks.
We want to try again. Should we do PGT testing? A further complicating factor is that, between the transfer last month and the positive test result, DH was diagnosed with a potentially serious genetic condition causing heart arrhythmia. We don't know yet if any other relatives have it or if DD does, which is obviously terrifying in itself.
Clinic are as surprised as we are that none of these have worked, there's nothing to indicate an issue, particularly given a smooth first successful pregnancy. DD was delivered by EMCS but that all looks fine internally and shouldn't cause any problems.
I need to talk to the clinic but what I'm thinking now is we do a round at as high dose meds as I can tolerate to get as many embryos as possible. Should we then PGT-A test? PGT-M for DH's condition? I've read conflicting things as to whether it's worth doing.
Supplement wise we are covered, I've read it starts with the egg. We are both taking Coq-10 (I stopped after transfer but will start again), DH is in Proxeed plus, zinc, and a multivitamin, I take a probiotic and am also on metformin prescribed via my clinic.
Any advice would be very gratefully received! Feeling a bit lost.