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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

IVF success stories with thyroid antibodies?

5 replies

Jupiteer · 11/12/2022 20:09

Hi all
We are due to start our first IVF cycle next month. 38yo, TTC 3yr with no BFP.
All our fertility tests are normal and we are therefore classed as unexplained.
I have Hashimotos underactive thyroid, I saw an endocrinologist several yrs ago when I was diagnosed and had high antibody levels on my blood test - can't remember the numbers. My TSH is ok currently as I am on thyroxine.
I asked the consultant at our NHS appt if the antibodies could be the cause of infertility / affect IVF, he didn't really answer the question and just said you are unexplained so we don't know.
However there are several studies I have found which do say there is a link between this and infertility / failed IVF which could be linked to antibodies in utero.
Has anyone had successful IVF with thyroid antibodies and no other treatment eg. Steroids? Looks like the NHS don't give them routinely.
Just looking for some hope going into the cycle so I don't feel it's doomed from the outset!

OP posts:
LouiseFox · 28/02/2023 08:45

Hi Jupiteer! I’m here looking for an answer to the same question - I’m so sorry not to be any help, but we are in the same boat at least. How did your IVF cycle go, I hope it went well? I had a freeze all cycle in January and am too nervous to do a transfer if my Hashimotos is the problem. Sending love.

Jupiteer · 10/03/2023 16:42

Hi @LouiseFox
I'm sorry I don't have any answers yet. My first cycle was cancelled prior to the egg collection due to over response, too many follicles and high oestridiol so they thought it was too risky to go ahead as would get severe OHSS. I doubt this is anything to do with my thyroid, just my overactive ovaries! I'm on stims again now on a different drug so fingers crossed. I'll definitely be having a freeze all cycle too. Hospital still don't seem bothered about the hashimotos and say don't worry about it 🙃
I hope all goes well for you, please keep me updated! x

OP posts:
Confusedkp · 07/07/2023 10:14

Hello, I would be interested to know the answer to this. I have hashimoto and did an FET in May but my thyroid TSH jumped up from 0.08 to 6.1 during the transfer period.

Jupiteer · 07/07/2023 15:13

Hi there
I am now 16 weeks pregnant following my 2nd IVF cycle and nobody seems bothered about my thyroid antibodies at all, and everything seems to be ok so far 🤞 hopefully that is reassuring for you!
Interestingly my TSH shot up after my transfer as well, it was less than 1 before starting the cycle and when it was checked at 6w pregnant it had gone up to 8!!! It must be the effect of the IVF drugs. I was concerned but increased my dose and it was back to normal by 10 weeks, still unsure how often to have it checked but seeing the midwife next week.
Good luck with your cycle @Confusedkp !
How did your FET go @LouiseFox ?

OP posts:
Sunflower360 · 18/03/2024 10:00

@Jupiteer hope you are well. Are you able to advise what protocol/meds were put in place for your Hashimotos when you had a BFP? I'm 38, first FET just failed and have thryoid antibodies. I was on Prednisolone during the FET. Thanks!

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