First round of IVF failed looking for some hope

[Sel86]

Hi there I am new to this and joined as really looking for some hope when I am feeling rock bottom.
we started our IVF treatment at the start of this month and went for our egg collection yesterday. We had a scan on the Friday before and we’re hopeful tho they’re were 6 large follicles. I have low AMH so this was a good result for us.
I did all the injections and trigger injection as advised but we were devastated yesterday to find that some of the larger follicles had gone (sounds like I already ovulated between Friday and weds) and of the couple of follicle left there were no eggs.
I feel so hopeless and like a failure that we can’t even get passed the egg collection stage let alone progress to getting any eggs actually fertilised and implanted.
I am looking to see if anyone else has been through the same and if there are any success stories from your future cycles.
We have waited this long to get here I can’t stand to think that is it and we are a lost cause now. We don’t have a consultants appointment until 3 weeks from now and I feel I will go insane between now and then without some idea there is still hope for us.
Any input would be massively appreciated 🙂

My friend has DOR, she went through a number of cycles to bank embryos and unfortunately in one of them she has spontaneous ovulation and in another no eggs were collected. These cycles were devastating, but she did manage to get results from other cycles. If you have DOR then you may want to look at clinics that specialise in DOR patients if you're not already under such a clinic.

Hi there,
Seen your post and had to comment. My first round ended the same way, meds appeared to be working up until day 7, day 9 was no further growth so they increased the dosage by which point it was too late. On my final scan day 12, they hadn’t progressed at all and some had even gone. As there was fluid and lining had reduced, they thought I had ovulated myself.
Next attempt was completely different, they upped the meds and I managed 14 follicles, only 2 of which survived blastocyst stage. 1 was implanted but unfortunately at 8 weeks we miscarried, that was 2 weeks ago. Luckily we still have a frozen one which I’m putting all my hopes on.
I was advised that a lot of first attempts fail as they only have information we give them on file so they judge the best they can, everyone reacts differently to meds, it’s kind of trail and error attempt I was told (but in a nice way).
After hearing this the first time I lost all hope but the second time as they had data to work with they got the meds spot on.
Please don’t lose hope, I'm sure next time around they will get it right for you and it will work perfectly.
Keep positive and relaxed (easier said than done I know lol )
All the best xx

@SH998 Thank you so much for your kind words it’s comforting to hear that others have been though the same thing and managed to get a better outcome the next time around. We have a call with a consultant from the clinic again tomorrow so hopping for some more guidance on what we can do. Hope all goes well and really sorry to hear about your miscarriage but fingers crossed for your frozen embryos xx

@Gardenlady543 thank you! That’s positive hear your friend did find success. We are with Care Sheffield having moved from leeds. The care seems much better to date but we are considering also speaking to a specialist from Kings in London who specialises in AMH.

Care is a chain, you'd likely need to travel to access a specialist in DOR. My friend recommends these clinics in London:

Kings fertility
Create
Evewell

She is with Dr Gudi at fertility plus who seems to be excellent.

I'm not sure if there are places that specialise in DOR outside of London.

It sounds like you have a plan with a discussion with your specialist and a consultation with a specialist clinic.

I have heard that spontaneous ovulation is very rare but it seems to happen more often in DOR than higher AFCs. It only happened to my friend once. Really sorry that you're going through this. I have heard there are some DOR support groups on Facebook m, it might be worth joining if you're not in them already.

Hi, I don’t have a success story I’m afraid but just wanted to reach out because I’ve been in a similar position (no eggs collected - didn’t ovulate early, just empty follicles) so I know how devastating and terrifying it is. I definitely think you have reason to stay hopeful. As others have said it’s your first cycle so your clinic will learn from it and hopefully a tweak in medication will make a big difference. Having confidence in your clinic is a big thing and hopefully they’ll give you a plan as to what they’ll do differently next time and you can start to look forward to that. I know 3 weeks seems forever to wait for your follow up appointment but having been there, I think it’s probably a good thing. It’ll give you time to get your head round things, maybe do some research and think of the questions you want to ask etc. Take care and be kind to yourself.

It is hard, sorry. If it helps, I had a few empty follicles in my round 1 and human growth hormone, steroids and a double trigger helped a lot on subsequent rounds in terms of numbers and not having empty ones. At the Evewell.

Hi OP, I've had a similar thing in my first cycle - 5 follicles going in and nothing collected - think I ovulated early. Was also delayed going in to EC.

I have DOR and moved to Create where I have had to do a number of cycles to get one egg per cycle usually and still some spontaneous ovulations but it's at least a big more protected as I have a scan before the EC to check if there's been any ovulation, so if I did then they would not go ahead with the EC and then the cycle was "preserved" for another try (although I have to pay for the blood tests, scans and medication ofc). They also do blood tests throughout so they are tracking LH (which keeps an eye on if you're looking likely to ovulate) and Oestrogen (which indicates if any of the follicles are likely to have eggs in). They also added in an extra Cetrotide shot for me when my LH rose to try and prevent early ovulation and also Indometacin to try to prevent the follicle rupturing. All in all, I feel in better hands with Create, although I have still had premature ovulation once or twice I think of one follicle but this was determined on the scan before the EC and we went ahead as the other follicle was still there.

So don't give up hope - maybe change clinics if your clinic doesn't agree to add blood tests or scans before EC to your plan.

Thank you @Rosiestraws thats reassuring to hear and hope all works out well for you!

How is everyone getting on in this thread - would love to hear some positive stories. Hoping all is well xx