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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Fresh ivf cycle after miscarriage

4 replies

Hopewishprayer · 24/04/2022 10:53

I recently had a miscarriage at what should have been 9 weeks. At 8 week scan we found out that the baby was measuring beging at just over 6 weeks and no obvious heartbeat. We are heartbroken but want to look to future and try another round.
This was out 2nd round of ICSI (MF) and our only embryo from 2 rounds so will be starting again with a fresh cycle. I have just turned 39 so feel the pressure of time massively and would like to get started as soon as possible.
I wondered if anyone has been in a similar situation and started a fresh round on next period? I am long protocol so I would have prostap day 21 following next period and then begin stims around a week later following a bleed from that.
Not sure if there would be any benefit to wait for a 2nd period to begin again and would appreciate hearing others experience x

OP posts:
SamE1 · 24/04/2022 19:15

My clinic likes you to have a bleed between, all depends on waiting list at the clinic too, they may not be able to get you in straight away for your follow up. Good luck!!

giraffesauce · 25/04/2022 14:09

Hi, I was in a very similar situation, got pregnant from a FET done after my 1st IVF cycle, ended in missed miscarriage at 10w (baby stopped growing at 9w). We had a couple of embryos left in the freezer but since we would like 2 children we decided to do another IVF cycle + fresh transfer right away.

I got my period exactly 4 weeks after my D&C, then started injections on day 2 of the next period (a month later). I don't think doctors will let you start injections unless you've had a full bleed in between.

That second IVF cycle was a bit of a disaster, our attrition rate was awful, but on day 5 we had one 3BB blast, which we transferred. I got pregnant and then had to have a termination at 14w due to a T21 diagnosis.

Pros:

  1. No time "wasted", if it doesn't work you can go into another cycle or a FET pretty quickly (of course this didn't end up being the case for me because I was pregnant for a whole 3.5 months and now I need to take a longer break anyway...).
  2. Your uterus is supposedly more receptive to implantation after a D&C.

Cons:

  1. Egg/sperm quality. I personally feel I went into this fresh cycle with suboptimal egg quality because 1) I had just been through the trauma of my first loss 2) during the pregnancy and after the loss my diet was awful (carbs & sugar were the only things I could keep down + emotional eating) and I hadn't exercised in months because of the exhaustion. I might be completely wrong here but I feel this contributed to the poor fertilisation and blastulation rate we had.
  2. Healing. I think there's value in waiting 2-3 months to process the loss and get back into a healthy mind&body shape.
  3. Testing & Knowledge. In hindsight I also think we should have taken the opportunity to do more testing after our 1st loss. It was confirmed to be monosomy X so I wish we would have done a Karyotype or at least decided to do PGS on our remaining embryos. This is what we are doing now but I wish it hadn't taken going through the pain of TFMR. You may want to look into further testing yourself before going into another transfer.

I totally understand that age also plays a part though, and the clock thing. What had your doctor advised?

Hopewishprayer · 27/04/2022 07:30

@giraffesauce thank you for replying and sharing your experience, I am very sorry for you losses, I hope that it works out for you in the end.
lots to think about, my rounds have not been great with embryo quality with only one viable embryo across 2 rounds so that is my concern that going 2 months later will cause it to be even worse than before.

OP posts:
IsabelHerna · 29/04/2022 21:09

I am so sorry for your loss x

I believe there needs to be a cycle in between the transfers, but I'm not sure.

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