Really High AMH Level

[MACLIL]

My AMH is 142, one of the highest our consultant has ever seen! We are due to start stims at the end of this month/beginning of next and I am really scared about possible OHHS. Would love to hear other peoples IVF experience with levels this high?

Hello!

Wow that is high, I had an AMH of 48 which was classed as high. I was put on a short protocol and I still had 38 follicles, I got very bloated after egg retrieval, but it went down in around 4 days so they still did the fresh transfer on day 5. I am now pregnant which is amazing but I did develop quite severe OHSS and honestly it was the worst thing I've ever been through, I was hospitalised for a week, couldn't stand up, I looked 9 months pregnant, could hardly breathe due to the fluid. I also have to take blood thinning injections for the full pregnancy. My ovaries were significantly enlarged due to the HCG keeping them over stimulated (still are enlarged). I'm home now at 7 weeks pregnant and the bloating has reduced slightly but I'm still uncomfortable, I believe it will start to fully disappear around 10-12 weeks when the placenta takes over. When the doctor told me that at 4 weeks I couldn't stop crying because it felt like a lifetime away.

My advice to you is to make sure you do a frozen cycle, I really wish I insisted on it. I know it drags things out but it's so worth it, I've been off work for 4 weeks and it's really been horrific.

A positive note is OHSS can be 100% avoided with the right decisions and high AMH respond very well to ivf (a bit too well) so that's a really good start, with close monitoring and a frozen transfer you should prevent OHSS but still get the results.

Hope this has helped, I wish someone that had had it advised me before transfer.

Sending lots of luck your way!

@Ashleighz88 Hi, thanks for getting back to me so quickly!

I know, so high. I've spent forever searching online for something similar and can't seem to find anyone with similar numbers.

You sound like you've had a dreadful time... I'm so sorry! It's one of those things that unless you're pushed into this world not many people are even aware it can happen. Glad you're at least back home... and also congratulations!

I'm have a scan this week and an appointment to talk things through with our clinic, so I'll for sure raise if a freeze all cycle is a good idea with these sorts of numbers. Such a high possibility of OHSS was one of the first things raised in our very first consultation and how they would need to err on the side of caution to try and avoid it at all costs, so I'm just keeping all my fingers crossed at this point!

Hi , my AMH was also really high >100 (clinic never gave me exact value) and I had a really high AFC of 160. I had a short protocol
And a freeze all cycle, after my first scan my medication doses were reduced as things were getting a bit risky. In the end I got a good result from STIMS and have 19 embryos frozen. I had to take blood thinners for 10 days after and the nurses from the clinic called me daily for the first week to check I wasn’t breathless etc. I think I was right at the edge of what the clinic would do risk wise, but they continued as I’m normal BMI and fit and healthy.

Hope it goes well for you!

Hi @MACLIL! I had AMH in the 140s as well, you’re the only person I’ve heard of with similar levels. I did have OHSS and felt pretty ill to be honest but avoided being hospitalised. Stock up on electrolyte drinks ahead of time. I had a frozen cycle for other reasons but I’m glad because it gave lots of time to recover. The good news is that you’re likely to respond well. I have ended up with 10 frozen embryos. I don’t know what will happen when we try to transfer them but I’m hoping it might mean that I don’t have to go through another egg retrieval cycle.