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PGS testing. Has anyone’s child suffered due to the biopsy of cells during PGS?

6 replies

Fs252 · 30/05/2021 09:59

I am pregnant following PGS testing of my day 5 blastocyst. I’ve been reading more into he limitations of PGS, bc I have been given a 1 in 5 chance of the baby having downs bc of a 3.5mm nuchal fold measurement at my 12 week scan. My bloods were clear. I’m 40, 39 at he time of fertilisation.

I am looking for experiences of children born after PGS. Are they developing well?

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andivfmakes3 · 30/05/2021 17:01

I've read of a few cases where the blastocyst was PGS normal but the baby subsequently tested positive for downs. Testing isn't 100% accurate as they only test the placenta cells and not the Baby ones

IslandStars · 30/05/2021 17:08

I’ve not heard of children suffering as a result of the biopsy and the procedure itself could not cause Downs, but of course, PGS can fail to spot a genetic problem as it’s not 100%, in the same way that mosaics can self correct and produce healthy babies.

Really hope everything works out fine, on the plus side, you have an 80% chance of your baby not having Downs.

Fs252 · 30/05/2021 17:12

Thanks for getting back to me. I’ve not actually read a post of someone this happened to, only that it has happened. Pls link any threads where I might read some, if that’s easy to do.

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Fs252 · 30/05/2021 17:14

Thanks @IslandStars.

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sozzleb1983 · 31/05/2021 22:59

Hello,
We had the testing of our frozen embryos and now have a very lively and healthy 10 month old little girl after a FET cycle. I would really recommend the testing as l definitely think it gave us more chance of success on the second cycle. Wishing you lots of luck x

Fs252 · 01/06/2021 07:42

@sozzleb1983. I've had PGS testing on my embryos and absolutely feel it helped in embryo selection, implantation and avoiding miscarriage. Ours worked first time. Glad to hear your daughter is happy and healthy. I've been googling way too much over the weekend following our awful combined test result

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