Low AMh - feeling down

[Bells3032]

Feeling a bit down over this weekend. I just never realised how long this whole process would take. It's now been two years since my husband started on the hormones (damage to his piturity due to cancer) - two years of waiting to find out whether ICSI would even be a possibility. In September his first SA with living sperm hurrah! i thought we could finally get going. had all my pre tests to find out my AMH is very low (5.8 at only 32). We wanted to do some embryo banking then but doctor said it wasn't necessary and sent me round the houses for a genetic test that apparently doesn't actually exist (Ehlers-Danos syndrome - there is a genetic test for it but not for the type they suspect i have hence the confusion).

then cos we wanted fresh transfer november and December cycles weren't possible cos of the bank holidays. Finally started late January and was told by the doctor he refused to do transfer cos I had gained 4lbs since September so insisted i lose 12lbs before he'll transfer.

When we only got 3 pgs normal blasts we saw Doctor's decision as a blessing and decided to do a couple more rounds of banking (despite the doctor's disagreement that we should - that doctor then left the clinic and the new one was more open to it). We have no idea whether my husband's meds will keep working and its making his blood very thick so keen for him to come off it asap. We agree 3 rounds would give us around 7-9 blasts which left us feeling more confident about having a second baby.

I also got my first covid vaccine in the meantime.

Second round last week and we only have 2 blasts this time and they still have to go through genetic testing.

Now worried that I will have to do 4 rounds or even more to get the numbers i want.

I don't understand why my AMH is so low. It's making me miserable. Everyone else in my family seem to be able to get pregnant by clicking their fingers. And by all checks with any other partner so would i. but it means poor response to IVF. No one in my family seems to be able to understand.

We had wanted to try and get pregnant in September 2020 and it looks like our first attempt won't even be til August 2021. I don't understand why my AMH is so low. it makes no sense.

I just want to cry but i don't want to make my DH feel bad for making me go through this.

You have 3 PGS tested normal blasts! That is amazing. I have low AMH and male factor infertility too and have done 5 rounds of IVF, it took us 3 rounds to get a blast in general which was negative, then we did a round of embryo banking which resulted in 3 blasts but none were normal and then another round which didn’t even make it to egg collection. Just had a scan for my 6th round and only 3 follicles.

With 3 PGS blasts I would start doing transfers. Each has a 70% chance of pregnancy.

It’s such a long process, I can see why you’re frustrated. You’ve had a greatly result in 3 PGS normal though and possibly another one to add from your last round. You should move onto transfers now, there’s no reason to try to bank more than 3+ PGS normal embryos at this stage.

I was told my euploid embryos had a 50-60% chance, but that’s possibly because I’m 42 and some consultants are just more cautious with their estimates. Sadly my first transfer didn’t work, but I have one more euploid left (took me 3 rounds to get 2 normal but I’m a lot older). Either way, the stats for PGS embryos are about as good as it gets with IVF, so I really think you have a great chance with 3 embryos.

thanks for your support.

My main concern is that what we get now is pretty much our only chance for babies and I want two kids. Once my husband comes off his meds we will have zero chance at ivf or natural conception and i don't want him staying on them for another 2 to 3 years as its getting dangerous for him. Plus my amh is so low but at the moment the quality is making up for it....it probably won't be the same in 2-3 years.

I just don't know how many is "enough" to make me feel confident we will have two kids from it. it's so hard to tell and doctor's won't give you a definite number