Wanting baby #2 genetic issues

[Boo2you]

I have PCOS but I'm currently having periods 35 week cycle to the day! I have been taking digital OPK's since 3 days after my period finished, so about two weeks and have still not had a positive result - I conceived easily almost 3 years ago and have a DD then same again two and a half years later however we had to end this pregnancy at 12 weeks due to severe medical reasons (can't have IVF as have a genetic condition I would need PGD but at £15k per cycle can't really afford). We've been Ttc #2 for 7 months not long I know but I'm 34 soon and I don't even know if I'm ovulating! I've not done the whole trying thing before as we've always got pregnant before we planned to try - I know I'm lucky to have my DD but my other issue is we only have a 50/50 chance of being able to continue with a pregnancy due to the genetic condition having severe consequences! Therefore we may need to try a few times before we get a healthy baby - don't really know what to do next anyone have any experience suggestions? All recent scans have shown no cysts currently on my ovaries!

I have PCOS and I don't get a positive OPK until about CD20, sometimes longer. Sounds likely in your case, especially given you have longer cycles. I'd keep going with the OPKs before you worry.

Hi OP have you been to your GP and discussed Chlomid? It's a common and cheap drug you take for a few set days after your bleed. Pretty much guarantees you ovulation. It could help with that element at least. Very common for people with PCOs. I'm not sure the clinic you got your ivf quote from but our cycle cost £5k inc drugs - all private. PGS testing was £900 per embryo. Good luck to you x

The PGD fee is set by NHS England so it's the same across the country unlike IVF - I would have had 3 free cycles but as we have an unaffected child we are now no longer entitled to funding. We went to an assisted conception clinic 2 years ago and were told it was £12k per cycle. We then spoke to them in March they said it had gone up to £15k per cycle and has a 1 in 3 success rate.

I'm going to my GP's soon does Clomid have any side affects and will I be able to get it if I'm having periods? I took cheap ovulation tests all most all of last month and didn't get any positive ones then either!

Also not relevant to this but do you know how I delete a post?

motherofdogscatschickens
Firstly, GPs don’t normally prescribe clomid. Secondly unless the OP isn’t ovulating clomid isn’t going to help. Thirdly if she does have PCOS she’s at increased risk of OHSS from clomid so it would probably be unwise for her to have it without monitoring. And fourthly her issue isn’t as far as we know with becoming pregnant (trying for 7 months is normal and she’s previously easily become pregnant twice), it’s having a baby with a genetic condition-clomid will do nothing to prevent or reduce the risk of this, only IVF with PGD will.

Clomid have any side affects and will I be able to get it if I'm having periods

It should not be prescribed by a GP as it requires specialist supervision. It can have serious side effects including OHSS and also increases the risk of multiple pregnancy (and all the complications which go with that).

It's is just because I conceived easily twice that I'm worried about why I'm not pregnant after 7 months, I know nothing but PGD will help the genetic condition and am worried that I'm not ovulating. Thanks for all your replies so far xx

Yes I have PCOS and wasn't allowed to be prescribed Clomid. It's unlikely that you'll be referred for fertility investigations until you've been trying for at least a year I'm afraid OP. I know it feels like ages but 7 months is pretty normal. Keep taking your OPKs and if you're certain you're not ovulating, check with your GP.

I tried for almost two years with no luck then had a break. Then conceived the baby I miscarried first time around. Then took 9 months to conceive my DD. Just because you've conceived very quickly before doesn't mean you will again, and that doesn't necessarily mean anything's wrong.

Another slight concern I have is because of complications related to the TFMR I had in October last year I had to have embolisation of the artery to the womb, this can cause the blood supply to the ovaries to stop if the blood supply is linked. Ovaries normally have their own blood supply and a scan I had two months after showed my ovaries looked normal presumably they wouldn't if they had 'died?!

I'm on CD 22 and finally got a positive OPK didn't expect to ovulate this late coz my last two pregnancies although I was on a 5 and 6 week cycle respectively I got pregnant two weeks after my period! The GP still wants to do some blood tests next week tho - I've now lost half a stone so I'm only 1lb over normal BMI but I want to lose another stone- with PCOS they check for insulin resistance which is what can contribute to weight gain!!

Are you able to go abroad? PGD is about €2k in Cyprus I believe.

May have to look into this thanks