PGD IVF

[123whatsmyusername]

Bit of a long story here..,
After 18 months TTC, DH and I conceived a baby, although at the 12 week scan concerns were raised about chromosomal abnormalities. Fast forward a few weeks and we learnt that I have an inversion on a chromosome, which caused our baby to be missing a significant amount of their same chromosome.
After much heartache, we decided the best option was to end the pregnancy (the risks posed to our baby’s life and development were too severe for any quality of life) and last week I delivered the most beautiful baby girl at 19 weeks pregnant.
We’ve been referred for PGD as there is a significant risk of this happening again in naturally conceived children.
My question is: does anybody have any experience of PGD as a result of chromosome inversions? Any success stories to share?

Hi, so sorry for loss of your baby girl. I went through an almost identical situation (although I was not so far along) a year ago. We found out that we are dealing with a balanced translocation, so not quite the same as an inversion but same idea and same result.
I am doing PGD now, so no success stories to share yet, and to be honest I am not feeling at all positive about my chances. But, it works for lots of people, and is also affected by usual IVF things such as your age (I am old!).
The best thing I can suggest is that you join the Facebook page, Balanced Translocation Support - it is full of amazing people and honestly the best support you will find on this. Don't worry about the group name, there are lots of people with inversions there too.
Thinking of you, it was such a shock to get our diagnosis and it's so soon after your loss

Thank you for your reply and I’m so sorry for your loss. I wouldn’t wish this on my worst enemy. I feel so alone - I’d never even heard of such conditions until a few weeks ago.
I’ve just requested to join the group. I’d just like to find out more about this.
Did you only discover the translocation after a natural conception? I’m terrified of conceiving naturally and having to go through this again.
Wishing you all the best for your PGD journey x

Yes, I discovered it after my TFMR. I've had 2 other MCs as well, one before we knew and one after when I think I was still in denial and thought it would be ok! We were told we could keep trying naturally as long as I felt I could keep having miscarriages.
The group will really help you, and also check out the Unique (rare chromo) web site for information leaflets. It's a lot to take in x