Progesterone suppositories

[Reiltin]

I've used progesterone suppositories twice now: first during the egg collection (transfer didn't go ahead) and then for the (failed) ivf cycle. Both times, it hasn't agreed with me. I got a uti the first time (never had one before) and something akin to cyctitis the second time (gp said it wasn't an infection but there was blood. The over-the-counter cyctitis medication didn't work: I had to take the prescription to get rid of whatever it was).

The problem is that the infection or almost-infection happens around the time of the transfer and once they cancelled the transfer and once they reluctantly did it and it failed. So I don't want to use it again in that way.

Has anyone taken progesterone in another way? Injected it, maybe? I'm waiting to speak with the clinic but thought I'd get some info from the hivemind first 😊

Progesterone injections do exist although I'm not sure how widely used they are in the UK. I believe they're intramuscular injections so more hardcore than subcutaneous ones for stims/downregging.

Bit of a blunt question, but were you using the progesterone vaginally or rectally? Some types you can do the latter and possibly this would reduce the issues you've been experiencing? Maybe something to ask your clinic about?

I was using it vaginally and the pack does say it can be used rectally so I imagine that's the next step.

Personally there is no way I'd consider intra muscular, ouch!
You can get Lubion in UK which is sub cutaneous once a day. It's expensive though, my clinic get reduced rates and it's £9.30 a day (so more than that if you don't get discount). That's £650 worth if you take it up until 12 weeks of pregnancy. So over 6x more expensive than pessaries by my calculations. I'm considering it as wondering if it's more effective than pessaries (just had a failed cycle so willing to try anything!).
Are you self funded or NHS? I'm not sure nhs would fund it.
Good luck xx

Out of interest, what brand of pessaries did you have?

I'd have thought the fiddling about of EC would be a factor. Maybe try the backdoor to see if that helps anyway.

I'm actually in Ireland and doing it privately. I'm using cyclogest.

I have heard you get the progesterone cream and injections but not sure how its available.

I'd try them rectally - I had no problem with them that way.

The injections are supposed to be very painful.
My clinic recommends buying an over the counter pessary for vaginal balance and using it at the same time as the progesterone pessaries. I'm not in the UK but maybe a chemist could point you towards something similar?
Perhaps also changing panty liner more often might help?

Sorry, realised you're not in the UK either.

Oh, cyclogest, it is much better rectally, less leakage so I would imagine less chance of irritation/infection.