I don't think the miracle 20th time lucky, don't give up hope comments are very helpful to be honest. Sorry. Yes i know it can work. But (sorry if I'm wrong), but the OP is asking for how to come to terms with the end of the road. Hope is a bastard when trying to come to terms with that, and hopeful stories are just cruel. She's been going through this for 18yrs FFS.
I had 6 attempts and no positive tests. We've got no known fertility issues but it just isn't working. We have "given up". Which means we have stopped trying anything medical, and stopped assuming it will happen one day. I'm nearly 41. And my DH's 44&1/2 year old sister has just had an unplanned baby. So i know it could happen, but I need to know it can't. I need to lose the hope. So that I can stop fucking wondering every single effing month whether maybe this sign or that sign might mean it is going to happen naturally. And to stop kidding myself that by stopping taking folic acid I am in fact just trying to tempt fate into getting me up the duff.
Hope is what makes it unbearable and impossible to move on.
So, OP. When do you decide it's the end of the road? Well, we just decided we weren't going to go through any more treatment because our lives had been on hold for too long. We set ourselves one last attempt, and planned a big trip for afterwards. It didn't work, and I found myself actually not being surprised that it failed. The earlier attempts I really thought the odds would be in our favour (20% success rate meant the more failures we had must surely mean the closer we were to succeeding...
) . But this time I truly was expecting it to fail. So it seemed a good time to stop, as I hazard lost faith in it ever working.
The trouble is I haven't lost hope that it might - naturally. I'm not sure how to move on properly while I still have that hope every time I go to the loo and can't stop myself doing knicker-watch.
Do you think this attempt will work? if you still do, then it's worth carrying on. Is the treatment different from before? Are they still learning from your results? But if you're getting to the stage where you feel you're just banging your head against a wall and you've tried all options available to you don't they say a sign of madness doing the same thing over and over and expecting a different response then you will know it is time to stop.