Please or to access all these features

Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Ivf idiots guide?

16 replies

FortyFacedFuckers · 27/02/2015 10:22

After 7 years of TTC #2 with one BFP which resulted in miscarriage. I am at the stage of deciding enough is enough or blowing our savings on Ivf.
I have always hated the thought of ivf the thought of all the tests, drugs, pills absolutely terrify me and I think I am absolutely petrified that it wouldn't work and I would be left devastated.
Most of all I think it's the fear of the unknown.
Is anyone willing to talk me through ivf (In simple terms) and tell me what it's really like?

---------------------

Hi there - this thread is a little old. [[https://www.mumsnet.com/conception/ivf
If you want to find out about IVF, we’ve got more information here]]. MNHQ

OP posts:
Persipan · 27/02/2015 11:09

I just came off a (failed, unfortunately) cycle of IVF. I actually have to say that the physical process was nowhere near as hardcore as I'd anticipated, and really wasn't bad at all - obviously it can vary from woman to woman but I basically felt fine throughout and kept wondering when it was going to start being as full-on as I anticipated, and it never did.

Other people have way more experience and can probably explain this better, but what basically happens is this. First off, you'd have some investigative tests to check things like what your egg reserve is like, whether you ovulate, what your lining is like, and so on. Expect, probably, some blood tests, a transvaginal ultrasound (colloquially known as 'dildo-cam' - it's undignified but nothing worse than that) and possibly your clinic may want to do some more tests involving minor procedures, depending on your history and their protocols. (For example, I ended up having to have a hysteroscopy - basically a tiny camera up through my lady-parts for a look at my uterus. It was no big deal and actually quite interesting).

When treatment starts, you'll self-administer medications (which your clinic will teach you how to do). You may have to sniff some of your meds; you will have to do some injections. This is not as big a thing as it sounds - you're probably hearing 'injections' and thinking Trainspotting, but they're generally subcutaneous (so, under your skin, not into a vein). They are basically impossible to do wrong! I didn't find them painful at all. Some women report side effects from the medications but again, I was fine.

You'll go and have regular scans (dildo-cam again!) while you take the medication to stimulate your ovaries. This is to check how everything is going, measure the number and size of developing follicles on your ovaries, and keep an eye on the lining of your uterus. As you approach egg retrieval, you might feel some discomfort if you have lots of follicles (because basically your ovaries get way bigger than normal).

When your clinic are happy with the size of the follicles, they'll instruct you to do a timed 'trigger' injection that prompts the eggs/folicles to get ready for ovulation. They then do your egg retrieval just before you ovulate (so you don't lose the eggs). This is basically a minor surgery, done under sedation. Most women find the process itself fine (whooo sedation!) but you may be uncomfortable afterwards. It essentially involves inserting a fine needle into your ovaries (through the vaginal wall) and hoovering out the eggs. You shouldn't need an overnight stay after your egg retrieval; in fact you can probably go home within a couple of hours. Some women are at risk of a condition called OHSS at this time - basically, where the ovaries have been overstimulated - which can cause discomfort and in some cases means further treatment has to be delayed while it's resolved.

Your eggs get mixed up with your partner's sperm in a Petri dish to fertilise (or, for some couples, they use a technique called ICSI, where they basically manually fertilise the eggs by selecting sperm cells and injecting then directly into the egg). It's likely that not all will fertilise at this stage. An embryologist then monitors their progress. Depending on your clinic and the number and quality of embryos you have, they will then transfer one (possibly two, in some circumstances) back into you on either the second, third or fifth day after you egg retrieval. Again, it's likely that not all will continue to develop over this time, of that some may be much better quality than others. Embryo transfer is pretty straightforward - no worse than getting a smear test done, really, though you do have to have a full bladder which makes it a bit uncomfortable. Basically, they pass a very fine catheter through your cervix and then whoosh your embryo in through that. You'll probably then be on progesterone to help support a pregnancy establishing (this might be a pessary or suppository, an injection, or a gel). If you have surplus embryos of high enough quality, they'll be frozen so you can use them for future attempts.

And then you wait two weeks to see if it worked. The two week wait, for my money, is the worst part of the whole process because there's nothing else to do but wait. And wait. And wait. Which brings us to the other side of the equation - the emotional impact. It's really hard to say how you may react emotionally, but the whole process can definitely be a roller-coaster because it's very high-stakes. At any stage in the process, things can go awry (no eggs retrieved, or none fertilised, or none make it to transfer) so it may not be straightforward. And you're right - it may not work. Your clinic should be able to give you got personal odds of success, but it's generally more likely that a round of IVF will be unsuccessful than that it will work (and in some cases an unsuccessful outcome is very much more likely).

My advice would be, think about going and having an initial consultation. You'll get the chance to ask questions and find out about your treatment options, and you aren't committing to anything by doing so. You may decide it's not for you, and that's fair enough; or it may be a chance to start the ball rolling.

Hope that's some help...

FortyFacedFuckers · 27/02/2015 11:15

Thank you some much for you answer.
So sorry it didn't work for you this time. Flowers

It does make it slightly less daunting knowing roughly what to expect. I hate the constant what if's and not knowing.

OP posts:
FortyFacedFuckers · 27/02/2015 11:20

Just to add I have endometriosis if the reason for infertility makes a difference.

OP posts:
Tootsiepops · 27/02/2015 11:34

I'm half way (egg collection tomorrow), so I can share what I've experienced so far. I was absolutely adamant I was not having ivf. Determined. I was overwhelmed by the thought of the needles, and I was horrified by pumping myself full of drugs. I've never even been on the pill and I barely take painkillers.

But, physically, it's been fine. I think I had built IVF up to be something akin to bloody chemotherapy. I did down regulation by tablet and nasal spray (four times per day, one sniff in each nostril) and it was a piece of piss. I had a bleed after I stopped the tablets, and then my injections started.

I did two subcutaneous jabs every night at 7pm with the smallest needles I've ever seen in my entire life (the size of a finger nail). The first night I did them, I was shaking so badly I gave myself several needle stick injuries. I can now do them without breaking a sweat and whilst making dinner at the same time.

I had my trigger shot last night. It stung a little, but that was all. I am aware of my ovaries when I move, but it's not painful. This might sound silly, but the thing I've found most difficult so far is scans on a full bladder. I've had several now and I've cried almost every time.

I think things may get a little more physically uncomfortable from here on in as I will be starting intramuscular progesterone injections in preparation for embryo transfer and I think they are supposed to sting a lot. The needles are pretty huge and I do feel very apprehensive about that. I also imagine that psychologically it's going to be tough because I am going to feel pregnant because of all the drugs even though I may not actually be pregnant.

I think I am pretty resigned to it not working out first time, but I do now know that I'm not afraid to do it again.

FortyFacedFuckers · 27/02/2015 11:56

Good luck tootsie

It's definately not sounding just as horrific as I had thought in my head. Thank you for sharing your experience so far.

OP posts:
Suitcase5 · 27/02/2015 16:02

Been lurking about here for a while and i am so glad someone has asked for the idiots guide! we have just been referred for IVF but have not once had everything explained to us by our doctors/gynae so it's a relief to hear this all spelled out black and white.

Thanks FortyFacedFuckers for asking the question im too much of a wimp to ask and thanks Persipan and Tootsiepops for sharing your experiences :)

4030ludders · 27/02/2015 20:49

Hi, I'm 42, one DD, 2 miscarriages, recently pregnant on 2nd cycle IVF.
One thing that doesn't get talked about often is how long the IVF long protocol (your own fresh, not frozen or donor eggs) takes. You notify the clinic on Day 1 of your cycle. You commence down regulation (when they suppress ovulation) around Day 21, for 2-3 weeks. You then stimulate for 10-14 days. Eggs are then collected under GA. They are then cultured for 2-5 days, depending on number, fertilisation rate, and their development. Then transferred back on either day 2, 3 or 5. Then the 2 week wait prior to pregnancy test. All in all this takes around 3 months.

Then you need to wait for 3 bleeds (around 2+ months) prior to starting another cycle. Some clinics say you can repeat a cycle immediately, but most, including mine, which is very evidence based and pioneered some of the current techniques, absolutely insist on you resting between cycles.

I found the first cycle ok, but was very tired during the 2nd cycle. I really think it varies by woman and life circumstances.

Zita West's book on Fertility and Assisted Conception outlines fertility advice for those TTC naturally and also the IVF process. You can discard her more holistic advice if you want, but the chapters on IVF explain current practice. Many clinics also have videos/powerpoint presentations, or open evenings.

Assume you have had the usual tests? Other factors to consider - your age, partner's age, strength of your relationship, etc...? We have described the physical process... but it can put a massive strain on you emotionally too. It's like the monthly wait, spread out over 3 months, intensified.

There is another recent thread on a similar topic. You will see the divergence in opinions! See www.mumsnet.com/Talk/infertility/2308469-41-and-about-to-start-either-IUI-or-IVF

lildottie · 27/02/2015 22:35

others have given the run down so ill just add i found the drugs, scans and procedures are easy. the emotional turmoil is a whole different game. but you're already going through that to some degree, and ivf isn't much worse than naturally failing to conceive month after month in that respect so "all" you have to lose is your savings. better to lose that than regret not trying though perhaps.

4030ludders · 28/02/2015 08:10

Should gave written, eggs are collected under sedation, not GA.

Tootsiepops · 28/02/2015 08:12

Sometimes under GA. I have egg collection this morning, and I'm having a general anaesthetic.

Not too sure how I feel about that to be honest...

Turquoisetamborine · 28/02/2015 08:25

Good luck Tootsiepops, hope it goes well.
Yes long protocol can be extremely long. My long protocol was 8 weeks from start to bfn. It was very, very hard emotionally. I turned into a very depressed person and couldn't face anyone. Not everyone is like that but the one person I know in real life who had ivf said the same thing.
I found short protocol much, much easier.

FortyFacedFuckers · 28/02/2015 12:11

Thank you all for the answers. I think being honest it is the emotional impact that scares me more than the treatment. I really feel at Rock bottom right now and I can't imagine going through all of that for another failure but then of course it could be the most wonderful thing I do.

OP posts:
4030ludders · 28/02/2015 12:43

You could have a prelim consultation - might help you ask questions, mull it over. Have you considered counselling, before / during? Many clinics offer this as they recognise the emotional strain ivf can bring.

FortyFacedFuckers · 28/02/2015 18:31

Yes I think I will consider going for a consultation to see if I can find out about ivf further.
I have been looking into counselling anyway to be honest I think I really need to help dealing with things whatever I decide to do.

OP posts:
AllTheNamesIWantHaveGone · 06/03/2015 07:44

I know you haven't asked for a book recommendation - but if you did fancy reading a guide to IVF then the Zita West one is quite a good read (it's called something like the 'Zita West Guide to Fertility and Assisted Conception').

Good luck OP.

FortyFacedFuckers · 06/03/2015 16:26

Thank you I will definately get that.

OP posts:
New posts on this thread. Refresh page