I'm too scared to drive through Paris - I have never driven on the right at all.
I had forgotten about Beaune; went there years ago and walked round the hopital, which was amazing.
Given my lack of confidence driving, I think I am looking for smaller places, though, such as bird parks, swimming lakes with sandy beaches, land trains around vineyards, etc, with chambres d'hote or small hotels nearby. Your ideas are certainly helping me to refine my ideas.
Timing depends a lot on relatives/friends with whom we will be staying. I am trying to work out an itinerary, then put it to them, then have to change the whole thing. Luckily in-laws have offered us their house in the country whether they are there or not (Hoping for not)
Have given us four days for Calais to Belleroche near Lyon, two days for the leg to somewhere-near-Pau and three-fours days for up to somewhere-near-Tours. Think it would be better not to try and drive South straight away on the first weekend of August, due to its reputation as driving hell, which is why I have given us time to hang about.
And yes, obviously, North West. Although I would love to visit Alsace one day.