I'm pretty sure we have bought Malarone OTC in SA, when I managed to lose some of our prescription on one trip. Think it was also cheaper than in the UK.
If you do buy in the UK, ring around for the best price. Our usual chemist charged more than double the other local chemist (£90 instead of £40 for the adult prescitpion - but was ever so slightly cheaper for the paediatric malarone). Guess which chemist we now avoid!
I would definitely take malarial tablets if you are going to the Kruger. Previously, in winter I owuld only have done so for the camps above Olifants, but I have been told that the malarial risk is now higher throughout the year and even at the southern camps. (something to do with a greater number of illegal immigriants coming through the park and also lower immunities 'cos of the prevalence of AIDS, so there is a greater pool of malaria carriers).
Are yuo going to the Kruger proper or to one of the adjoining private reserves? If it is the Kruger, then, to address MollieO's concern, it is self drive, so you can take children of any age. You are in your own car and can control how long you spend driving about according to your kids' attention span.
Ds has now been 3 times: first time when he was just 13 months old (0bviously, more for his mum and Dad than for him! ), second time when he was 4 years old, which he really enjoyed and then last year, when he was 8, so he is now an old hand.
Whereabouts will you be staying in the Kruger?